@inproceedings{10.1117/12.906148,
author = {Sebastian Marschall and Thomas Klein and Wolfgang Wieser and Teresa Torzicky and Michael Pircher and Benjamin R. Biedermann and Christian Pedersen and Christoph K. Hitzenberger and Robert Huber and Peter E. Andersen},
title = {{Broadband Fourier domain mode-locked laser for optical coherence tomography at 1060 nm}},
volume = {8213},
booktitle = {Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVI},
editor = {Joseph A. Izatt and James G. Fujimoto and Valery V. Tuchin},
organization = {International Society for Optics and Photonics},
publisher = {SPIE},
pages = {82130R},
abstract = {Optical coherence tomography (OCT) in the 1060nm range is interesting for in vivo imaging of the human
posterior eye segment (retina, choroid, sclera) due to low absorption in water and deep penetration into the
tissue. Rapidly tunable light sources, such as Fourier domain mode-locked (FDML) lasers, enable acquisition
of densely sampled three-dimensional datasets covering a wide field of view. However, semiconductor optical
amplifiers (SOAs)-the typical laser gain media for swept sources-for the 1060nm band could until recently
only provide relatively low output power and bandwidth. We have implemented an FDML laser using a new SOA
featuring broad gain bandwidth and high output power. The output spectrum coincides with the wavelength
range of minimal water absorption, making the light source ideal for OCT imaging of the posterior eye segment.
With a moderate SOA current (270 mA) we achieve up to 100nm total sweep range and 12 μm depth resolution
in air. By modulating the current, we can optimize the output spectrum and thereby improve the resolution to
9 μm in air (~6.5 μm in tissue). The average output power is higher than 20mW. Both sweep directions show
similar performance; hence, both can be used for OCT imaging. This enables an A-scan rate of 350 kHz without
buffering the light source output.},
keywords = {optical coherence tomography, tunable laser, swept source, Fourier domain mode-locking, broadband semiconductor optical amplifier},
year = {2012},
doi = {10.1117/12.906148},
URL = {https://doi.org/10.1117/12.906148}
}

@inproceedings{10.1117/12.908798,
author = {Thomas Klein and Wolfgang Wieser and Raphael Andr{\'e} and Tom Pfeiffer and Christoph M. Eigenwillig and Robert Huber},
title = {{Multi-MHz FDML OCT: snapshot retinal imaging at 6.7 million axial-scans per second}},
volume = {8213},
booktitle = {Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVI},
editor = {Joseph A. Izatt and James G. Fujimoto and Valery V. Tuchin},
organization = {International Society for Optics and Photonics},
publisher = {SPIE},
pages = {82131E},
abstract = {We demonstrate the acquisition of densely sampled wide-field 3D OCT datasets of the human retina in 0.3s. This
performance is achieved with a multi-MHz Fourier domain mode-locked (FDML) laser source operating at 1050nm. A two-beam
setup doubles the 3.35MHz laser sweep rate to 6.7MHz, which is 16x faster than results achieved with any non-FDML
source used for retinal OCT. We discuss two main benefits of these high line rates: First, large datasets over an ultra-wide
field of view can be acquired with a low probability of distortions. Second, even if eye movements occur, now the scan rate
is high enough to directly correct even the fastest saccades without loss of information.},
keywords = {Optical coherence tomography, OCT, MHz OCT, Fourier-domain mode-locking, FDML, retinal imaging},
year = {2012},
doi = {10.1117/12.908798},
URL = {https://doi.org/10.1117/12.908798}
}

@inproceedings{10.1117/12.909830,
author = {Cedric Blatter and Branislav Grajciar and Robert Huber and Rainer A. Leitgeb},
title = {{Deep skin structural and microcirculation imaging with extended-focus OCT}},
volume = {8207},
booktitle = {Photonic Therapeutics and Diagnostics VIII},
editor = {Anita Mahadevan-Jansen and E. Duco Jansen and Andreas Mandelis and Kenton W. Gregory M.D. and Guillermo J. Tearney M.D. and Laura Marcu and Nikiforos Kollias and Bernard Choi and Haishan Zeng and Melissa J. Suter and Stephen Lam and Matthew Brenner and Hyun Wook Kang and Bodo E. Knudsen M.D. and Henry Hirschberg M.D. and Steen Madsen and Brian Jet-Fei Wong M.D. and Justus F. Ilgner M.D. and Krzysztof Izdebski},
organization = {International Society for Optics and Photonics},
publisher = {SPIE},
pages = {82070B},
abstract = {We present an extended focus OCT system for dermatologic applications that maintains high lateral resolution over a
large depth range by using Bessel beam illumination. More, Bessel beams exhibit a self-reconstruction property that is
particularly useful to avoid shadowing from surface structures such as hairs. High lateral resolution and high-speed
measurement, thanks to a rapidly tuning swept source, allows not only for imaging of small skin structures in depth but
also for comprehensive visualization of the small capillary network within the human skin in-vivo. We use this
information for studying temporal vaso-responses to hypothermia. In contrast to other perfusion imaging methods such
as laser Doppler imaging (LDI), OCT gives specific access to vascular responses in different vascular beds in depth.},
keywords = {Optical Coherence Tomography, FDML Swept Source, Extended focus, Bessel beam, Self-reconstruction property, Microcirculation imaging, Vasomechanics},
year = {2012},
doi = {10.1117/12.909830},
URL = {https://doi.org/10.1117/12.909830}
}

@inproceedings{10.1117/12.908148,
author = {Desmond C. Adler and Wolfgang Wieser and Francois Trepanier and Joseph M. Schmitt and Robert A. Huber},
title = {{Coherence length extension of Fourier domain mode locked lasers}},
volume = {8213},
booktitle = {Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVI},
editor = {Joseph A. Izatt and James G. Fujimoto and Valery V. Tuchin},
organization = {International Society for Optics and Photonics},
publisher = {SPIE},
pages = {82130O},
abstract = {Fourier domain mode locked (FDML) lasers provide high sweep rates, broad tuning ranges, and high output powers for
optical coherence tomography (OCT) systems. However, presently-known FDML lasers at 1300 nm have relatively
short coherence lengths, limiting the size of samples that can be imaged. Furthermore, FDML lasers produce only one
useable sweep direction. We report FDML coherence length extension by incorporating advanced dispersion
compensation modules (DCMs). DCMs eliminate group velocity dispersion in the cavity, doubling coherence lengths
and ensuring uniform axial resolution over the imaging range. Additionally, forward and backward sweeps are nearly
identical, removing the need for external buffering stages.},
keywords = {Fourier domain mode locked lasers, FDML, swept source, optical coherence tomography, dispersion compensation},
year = {2012},
doi = {10.1117/12.908148},
URL = {https://doi.org/10.1117/12.908148}
}

@INPROCEEDINGS{2012SPIE.8213E..23H,
   author = {{Hagen-Eggert}, M. and {Koch}, P. and {H{\"u}ttmann}, G.},
    title = "{Analysis of the signal fall-off in spectral domain optical coherence tomography systems}",
booktitle = {Society of Photo-Optical Instrumentation Engineers (SPIE) Conference Series},
     year = 2012,
   series = {Society of Photo-Optical Instrumentation Engineers (SPIE) Conference Series},
   volume = 8213,
    month = feb,
      doi = {10.1117/12.910921},
   adsurl = {http://adsabs.harvard.edu/abs/2012SPIE.8213E..23H},
  adsnote = {Provided by the SAO/NASA Astrophysics Data System}
}

@inproceedings{10.1117/12.911443,
author = {Cedric Blatter and Branislav Grajciar and Boris Hermann and Robert Huber and Wolfgang Drexler and Rainer A. Leitgeb},
title = {{Simultaneous dark-bright field swept source OCT for ultrasound detection}},
volume = {8213},
booktitle = {Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVI},
editor = {Joseph A. Izatt and James G. Fujimoto and Valery V. Tuchin},
organization = {International Society for Optics and Photonics},
publisher = {SPIE},
pages = {82131M},
abstract = {We introduce a swept source FDOCT imaging system that allows measuring simultaneously the reflected light and
scattered light (bright field) and the scattered light only (dark field) in two different channels through separate Gaussian
and Bessel detection. Specular reflections can then be used to obtain knowledge about the sample time evolution with
high SNR for phase analysis. Based on this configuration, we provide a proof-of principle study for resolving ultrasound
pulse trains with high temporal resolution on surfaces, which potentially provides a novel phase sensitive all optical
detection scheme for the combination of OCT with photoacoustic imaging.},
keywords = {Dark field imaging, Bessel beam, Extended focus, FDML Swept Source, Multichannel detection, Photoacoustic, Ultrasound, Phase sensitive},
year = {2012},
doi = {10.1117/12.911443},
URL = {https://doi.org/10.1117/12.911443}
}

@inproceedings{Hagen-Eggert,
   author = {Hagen-Eggert, M. and Koch, P. and Huttmann, G.},
   title = {Analysis of the signal fall-off in spectral domain optical coherence tomography systems},
   editor = {Joseph, A. Izatt and James, G. Fujimoto and Valery, V. Tuchin},
   publisher = {SPIE},
   volume = {8213},
   pages = {82131K},
url = {https://doi.org/10.1117/12.910921},
   year = { 2012}

}

@inproceedings{
   author = {Just, T. and Wiechmann, T. and Stachs, O. and Stave, J. and Guthoff, R. and Huttmann, G. and Pau, H. W.},
   title = {Confocal endomicroscopy of the larynx},
   editor = {Nikiforos, Kollias and Bernard, Choi and Haishan, Zeng and Hyun Wook, Kang and Bodo, E. Knudsen and Brian Jet-Fei, Wong and Justus, F. Ilgner and Krzysztof, Izdebski and Melissa, J. Suter and Stephen, Lam and Matthew, Brenner and Kenton, W. Gregory and Guillermo, J. Tearney and Laura, Marcu and Henry, Hirschberg and Steen, Madsen and Anita, Mahadevan-Jansen and Jansen, E. Duco and Andreas, Mandelis},
   publisher = {SPIE},
   volume = {8207},
   pages = {82072H},

}

@inproceedings{Otte2012,
   author = {Otte, Christoph and Huttmann, Gereon and Schlaefer, Alexander},
   title = {Feasibiliy of optical detection of soft tissue deformation during needle insertion},
   editor = {David, R. Holmes, III and Kenneth, H. Wong},
   publisher = {SPIE},
   volume = {8316},
   pages = {83160V},
year = { 2012},
url = { https://www.spiedigitallibrary.org/conference-proceedings-of-spie/8316/83160V/Feasibiliy-of-optical-detection-of-soft-tissue-deformation-during-needle/10.1117/12.912538.short}

}

@inproceedings{Franke-2012,
   author = {Franke, Gesa Lilith and Hillmann, Dierck and Claussen, Thorsten and Luhrs, Christian and Koch, Peter and Huttmann, Gereon},
   title = {High resolution holoscopy},
   editor = {Joseph, A. Izatt and James, G. Fujimoto and Valery, V. Tuchin},
   publisher = {SPIE},
   volume = {8213},
   pages = {821324},
URL = { https://doi.org/10.1117/12.911166},
year = { 2012}

}

@inproceedings{Hüttmann2012,
   author = {Hüttmann, G. and Orzekowsky-Schröder, R.},
   title = {Imaging of immune cell dynamics in small intestine and the eye  by 2-photon microcopy},
   booktitle = {7th Workshop on Advanced Multiphoton and Fluorescence Lifetime Imaging Techniques (FLIM 2012)},
year = { 2012},
   abstract = {Autofluorescence based 2-photon microscopy was investigated as a
tool for studying the dynamics of immunological processes in vivo. Nearly
all tissue components were simultaneously visible by autofluorescence and a
nearly complete visualization of tissue architecture was possible. Within
the tissue, immune competent cells like lymphocytes, macrophages and
dendritic cells were visualized in their dynamic interaction with other
cells or surrounding tissues.
Immunological processes were studied in the small intestine and at the
surface of the eye. Excitation and emission spectra of the different mucosal
tissue components were quantitatively determined and a compared to the
respective spectra of endogenous chromophores. It was shown, that by using
only two excitation wavelengths within the tuning range of a Ti:Saphire
laser enterocytes, antigen presenting cells and lysosomes of the small
intestine could be discriminated based on the excitation and emission
properties. By additionally using an intravital nuclear stain, motion of
lymphocytes in the lamina propria and the epithelium of small intestine
villi was quantitatively analyzed. 

2-photon microscopy was also a powerful tool for studying the conjunctiva
and cornea of the eye. Lymphocyte dynamics and uptake of microspheres or
fluorescing heat-inactivated E. coli was followed over time in the
conjunctiva-associated lymphoid tissue of mice. In a different mouse model
of suture induced corneal hem- and lymphangiogenesis, immune cell migration
into lymphatic vessels and luminal transport of individual cells was
observed in vivo.

Autofluorescence based 2-photon intravital microscopy is a valuable tool to
study dynamic immunological processes. While tissue autofluorescence gives a
good overview over all relevant structures and allows for discriminating
different cell types by spectral analysis, the additional combination of
specific staining with external dyes or fluorescent proteins is easily
possible and enhances the potential of the technique further. },

}

@inproceedings{Spahr2012,
   author = {Spahr, Hendrik and Rudolph, Linda and Muller, Heike and Birngruber, Reginald and Huttmann, Gereon},
   title = {Imaging of photothermal tissue expansion via phase sensitive optical coherence tomography},
   editor = {Joseph, A. Izatt and James, G. Fujimoto and Valery, V. Tuchin},
   publisher = {SPIE},
   volume = {8213},
   pages = {82131S},
year = { 2012},
url = { https://doi.org/10.1117/12.911429}

}

@inproceedings{Ansari2012,
   author = {Ansari, Rehman and Aherrahrou, Redouane and Aherrahrou, Zouhair and Erdmann, Jeanette and Huttmann, Gereon and Schweikard, Achim},
   title = {Quantitative analysis of cardiomyocyte dynamics with optical coherence phase microscopy},
   editor = {Joseph, A. Izatt and James, G. Fujimoto and Valery, V. Tuchin},
   publisher = {SPIE},
   volume = {8213},
   pages = {821338},
year = { 2012},
url = {https://doi.org/10.1117/12.911781}

}

@inproceedings{Klein:11,
author = {Thomas Klein and Wolfgang Wieser and Benjamin R. Biedermann and Christoph M. Eigenwillig and Robert Huber},
booktitle = {CLEO:2011 - Laser Applications to Photonic Applications},
journal = {CLEO:2011 - Laser Applications to Photonic Applications},
keywords = {Optical coherence tomography; Lasers, tunable; Image quality; Imaging techniques; Laser modes; Medical imaging; Mode locking; Optical coherence tomography},
pages = {CWB1},
publisher = {Optica Publishing Group},
title = {FDML laser for megahertz retinal OCT imaging},
year = {2011},
url = {https://opg.optica.org/abstract.cfm?URI=CLEO_SI-2011-CWB1},
doi = {10.1364/CLEO_SI.2011.CWB1},
abstract = {A novel Fourier-domain mode locked (FDML) laser design is presented, yielding the highest wavelength sweep speed reported so far around 1050nm. This enables retinal imaging over a ~70{\textdegree} ultra-wide field of view.},
}

@inproceedings{10.1117/12.889669,
author = {Cedric Blatter and Branislav Grajciar and Christoph M. Eigenwillig and Wolfgang Wieser and Benjamin R. Biedermann and Robert Huber and Rainer A. Leitgeb},
title = {{High-speed functional OCT with self-reconstructive Bessel illumination at 1300 nm}},
volume = {8091},
booktitle = {Optical Coherence Tomography and Coherence Techniques V},
editor = {Rainer A. Leitgeb and Brett E. Bouma},
organization = {International Society for Optics and Photonics},
publisher = {SPIE},
pages = {809104},
abstract = {We present a Bessel beam illumination FDOCT setup with FDML buffered swept source at 1300nm. An extended focus
is achieved due to the Bessel beam that preserves its lateral extend over a large depth range. Decoupling the illumination
from the Gaussian detection improves the sensitivity as compared to double passing the ring filter and enables dark field
imaging. Dark field imaging is useful to avoid strong reflexes from the sample's surface that adversely affect the
sensitivity due to the limited dynamic range of high-speed 8bit acquisition cards. Furthermore, Bessel beams exhibit a
self-reconstruction property that allows imaging even behind obstacles such as hairs on skin.
Densely sampled volumes of skin in-vivo with high lateral resolution are acquired at up to 440kHz A-Scan rate. In
addition the possibility of contrasting capillaries with high sensitivity is shown, using inter-B-scan speckle variance
analysis. High-speed imaging is of crucial importance for imaging small details since sample motion artifacts are
reduced and high sampling can be maintained while increasing the B-Scan rate.},
keywords = {Extended focus, Bessel beam, Self-reconstructive illumination, Dark field imaging, Dermatology, Microcirculation imaging, FDML, Swept Source},
year = {2011},
doi = {10.1117/12.889669},
URL = {https://doi.org/10.1117/12.889669}
}

@inproceedings{10.1117/12.875594,
author = {Cedric Blatter and Branislav Grajciar and Robert Huber and Rainer A. Leitgeb},
title = {{Structural and functional imaging with extended focus dark-field OCT at 1300nm}},
volume = {7889},
booktitle = {Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XV},
editor = {James G. Fujimoto and Joseph A. Izatt and Valery V. Tuchin},
organization = {International Society for Optics and Photonics},
publisher = {SPIE},
pages = {78891D},
abstract = {We present an extended focus FDOCT setup with FDML swept source centered at 1310nm. The illumination, preserving
its lateral extend over a large depth range thanks to the use of a Bessel beam, is decoupled from the Gaussian detection in
order to increase the global sensitivity. The efficient spatial separation enables dark-field imaging. In-vivo measurements
in the skin were performed to demonstrate the gain in lateral resolution while preserving the imaging depth. More, the
calculation of the speckle variance between B-Scans allows a clear visualization of the microvasculature.},
keywords = {Extended focus, Dark Field imaging, Bessel beam, FDML Swept Source, dermatology, microvascularisation imaging},
year = {2011},
doi = {10.1117/12.875594},
URL = {https://doi.org/10.1117/12.875594}
}

@inproceedings{Hüttmann2011,
   author = {Hüttmann, Gereon and Rahmanzadeh, Ramtin and Rudnitzki, Florian and Endl, Elmar and Hasan, Tayyaba},
   title = {Targeted molecular effects through laser-irradiated nanoabsorbers},
   editor = {Newsrrom, SPIE},
   DOI = {10.1117/2.1201102.003548},
   type = {Conference Proceedings},
   year = { 2011}
}

@inproceedings{Bonin2011,
   author = {Bonin, Tim and Koch, Peter and Huttmann, Gereon},
   title = {Comparison of fast swept source full-field OCT with conventional scanning OCT},
   editor = {Rainer, A. Leitgeb and Brett, E. Bouma},
   publisher = {SPIE},
   volume = {8091},
   pages = {80911K},
year = { 2011}

}

@inproceedings{Hagen-Eggert2011,
   author = {Hagen-Eggert, M. and Hillmann, D. and Koch, P. and Huttmann, G.},
   title = {Diffusion-sensitive Fourier-domain optical coherence tomography},
   editor = {James, G. Fujimoto and Joseph, A. Izatt and Valery, V. Tuchin},
   publisher = {SPIE},
   volume = {7889},
   pages = {78892B},

}

@inproceedings{Fritz2011,
   author = {Fritz, Andreas and Zegelin, Andrea and Ptaszynski, Lars and Birngruber, Reginald and Brinkmann, Ralf},
   title = {Dynamics of laser induced micro bubble clusters on tissue phantoms},
   volume = {7885},
   pages = {78850S-78850S-6},
   note = {10.1117/12.875031},
   abstract = {Selective retina treatment (SRT) is a laser based method to treat retinal diseases associated with disorders of the retinal pigment epithelium (RPE) while preserving photoreceptors and choroid. Applying microsecond laser pulses to the 100- 200 strongly absorbing melanin granules inside the RPE cells induces transient micro bubbles which disrupt the cells. Aim of this work is to understand bubble dynamics in clusters with respect to the influence of the adjacent retina. Bubble dynamics were investigated in vitro on porcine RPE. An about 200 μm thick layer of agarose gel was applied to the RPE layer in order to simulate the mechanical properties of retina. Different laser pulse durations from 1 ns (532 nm, Nd:YAG) to 1.7 μs (527 nm, Nd:YLF) were used. The bubbles were investigated interferometrically (fiber interferometer @ 830 nm) and with fast flash photography (25 ns flash duration). Bubble lifetimes were measured. The results show that with retina phantoms the bubble formation threshold was reached at 2.5 times higher irradiation than without retina phantom for 1.7 μs laser pulses. The microbubbles generated with 1 ns laser pulses were almost not influenced by the agarose layer. Irradiation twofold over bubble formation threshold resulted in 3.5 times longer bubble lifetimes for μs and 2 times longer for ns pulse durations, respectively.},
   url = {https://www.spiedigitallibrary.org/conference-proceedings-of-spie/7885/1/Dynamics-of-laser-induced-micro-bubble-clusters-on-tissue-phantoms/10.1117/12.875031.short},
   type = {Conference Proceedings},
year = { 2011}
}

@inproceedings{Hillmann2011,
   author = {Hillmann, Dierck and Luhrs, Christian  and Bonin, Tim  and Koch, Peter and Vogel, Alfred  and Huttmann, Gereon },
   title = {Holoscopy: holographic optical coherence tomography},
   editor = {Rainer, A. Leitgeb and Brett, E. Bouma},
   publisher = {Proc. SPIE},
   volume = {8091},
   pages = {80911H},
   url = {http://link.aip.org/link/?PSI/8091/80911H/1
http://dx.doi.org/10.1117/12.889485},
   type = {Conference Proceedings},
year = { 2011}
}

@inproceedings{Müller-2011-2,
   author = {Muller, Heike H. and Ptaszynski, Lars and Schlott, Kerstin and Bonin, Tim and Bever, Marco and Koinzer, Stefan and Birngruber, Reginald and Brinkmann, Ralf and Huttmann, Gereon},
   title = {Imaging of temperature distribution and retinal tissue changes during photocoagulation by high speed OCT},
   editor = {James, G. Fujimoto and Joseph, A. Izatt and Valery, V. Tuchin},
   publisher = {SPIE},
   volume = {7889},
   pages = {78890E},
URL = { https://doi.org/10.1117/12.874788},
year = { 2011}

}

@inproceedings{Just2011,
   author = {Just, T. and Pau, H. W. and Lankenau, E. and Huttmann, G.},
   title = {OCT in the field of laryngology: further perspectives},
   editor = {Nikiforos, Kollias and Bernard, Choi and Haishan, Zeng and Hyun Wook, Kang and Bodo, E. Knudsen and Brian, J. Wong and Justus, F. R. Ilgner and Kenton, W. Gregory and Guillermo, J. Tearney and Laura, Marcu and Henry, Hirschberg and Steen, J. Madsen and Andreas, Mandelis and Anita, Mahadevan-Jansen and Jansen, E. Duco},
   publisher = {SPIE},
   volume = {7883},
   pages = {78831W},
Year = { 2011}

}

@inproceedings{Schlott2011,
   author = {Schlott, Kerstin and Koinzer, Stefan and Ptaszynski, Lars and Luft, Susanne and Baade, Alex and Bever, Marco and Roider, Johann and Birngruber, Reginald and Brinkmann, Ralf},
   title = {Optoacoustic temperature determination and automatic coagulation control in rabbits},
   booktitle = {Ophthalmic Technologies XXI },
   editor = {Ho, Fabrice Manns; Per G. Söderberg; Arthur},
   publisher = {Proc. SPIE},
   volume = {7885},
   note = {10.1117/12.875104},
   abstract = {Retinal laser photocoagulation is an established treatment method for many retinal diseases like macula edema or diabetic retinopathy. The selection of the laser parameters is so far based on post treatment evaluation of the lesion size and strength. Due to local pigment variations in the fundus and individual transmission the same laser parameters often lead to an overtreatment. Optoacoustic allows a non invasive monitoring of the retinal temperature increase during retinal laser irradiation by measuring the temperature dependent pressure amplitudes, which are induced by short probe laser pulses. A 75 ns/ 523 nm Nd:YLF was used as a probe laser at a repetition rate of 1 kHz, and a cw / 532 nm treatment laser for heating. A contact lens was modified with a ring-shaped ultrasonic transducer to detect the pressure waves at the cornea. Temperatures were collected for irradiations leading to soft or invisible lesions. Based on this data the threshold for denaturation was found. By analyzing the initial temperature increase, the further temperature development during irradiation could be predicted. An algorithm was found to calculate the irradiation time, which is needed for a soft lesion formation, from the temperature curve. By this it was possible to provide a real-time dosimetry by automatically switching off the treatment laser after the calculated irradiation time. Automatically controlled coagulations appear softer and more uniformly.},
   keywords = {AutoPhoN},
   url = {http://dx.doi.org/10.1117/12.875104},
   type = {Conference Proceedings},
year = { 2011}
}

@inproceedings{Horstmann2011,
   author = {Horstmann, Jens and Baade, Alexander and Brinkmann, Ralf},
   title = {Photoacoustic blood vessel detection during surgical laser interventions},
   publisher = {SPIE ECBO},
   volume = {8092},
   pages = {80920Z-80920Z-6},
   note = {10.1117/12.889635},
   abstract = {This paper presents a discussion about the potential of photoacoustics with regard to its application in surgical assistance during minimally invasive, laser assisted interventions. Aim of the work is the detection of obscured large blood vessels in order to prevent unintentional dissection. Based on spectroscopic investigations of the target tissue (liver), a wavelength for the photoacoustic excitation laser was chosen with respect to a high absorption contrast between the vessel and the surrounding liver tissue. An experimental setup featuring a simple liver model is created. Preliminary results show, that vessels with a diameter of 2 mm can be detected up to a distance of 1 mm from the treatment fibre. It is shown, that detection of acoustic waves induced inside liver is feasible over distances higher than 10 cm.},
   url = {http://dx.doi.org/10.1117/12.889635},
   type = {Conference Proceedings},
year = { 2011}
}