@inproceedings{Ansari2012,
   author = {Ansari, Rehman and Aherrahrou, Redouane and Aherrahrou, Zouhair and Erdmann, Jeanette and Huttmann, Gereon and Schweikard, Achim},
   title = {Quantitative analysis of cardiomyocyte dynamics with optical coherence phase microscopy},
   editor = {Joseph, A. Izatt and James, G. Fujimoto and Valery, V. Tuchin},
   publisher = {SPIE},
   volume = {8213},
   pages = {821338},
year = { 2012},
url = {https://doi.org/10.1117/12.911781}

}

@INPROCEEDINGS{2012SPIE.8213E..23H,
   author = {{Hagen-Eggert}, M. and {Koch}, P. and {H{\"u}ttmann}, G.},
    title = "{Analysis of the signal fall-off in spectral domain optical coherence tomography systems}",
booktitle = {Society of Photo-Optical Instrumentation Engineers (SPIE) Conference Series},
     year = 2012,
   series = {Society of Photo-Optical Instrumentation Engineers (SPIE) Conference Series},
   volume = 8213,
    month = feb,
      doi = {10.1117/12.910921},
   adsurl = {http://adsabs.harvard.edu/abs/2012SPIE.8213E..23H},
  adsnote = {Provided by the SAO/NASA Astrophysics Data System}
}

@inproceedings{Hagen-Eggert,
   author = {Hagen-Eggert, M. and Koch, P. and Huttmann, G.},
   title = {Analysis of the signal fall-off in spectral domain optical coherence tomography systems},
   editor = {Joseph, A. Izatt and James, G. Fujimoto and Valery, V. Tuchin},
   publisher = {SPIE},
   volume = {8213},
   pages = {82131K},
url = {https://doi.org/10.1117/12.910921},
   year = { 2012}

}

@inproceedings{
   author = {Just, T. and Wiechmann, T. and Stachs, O. and Stave, J. and Guthoff, R. and Huttmann, G. and Pau, H. W.},
   title = {Confocal endomicroscopy of the larynx},
   editor = {Nikiforos, Kollias and Bernard, Choi and Haishan, Zeng and Hyun Wook, Kang and Bodo, E. Knudsen and Brian Jet-Fei, Wong and Justus, F. Ilgner and Krzysztof, Izdebski and Melissa, J. Suter and Stephen, Lam and Matthew, Brenner and Kenton, W. Gregory and Guillermo, J. Tearney and Laura, Marcu and Henry, Hirschberg and Steen, Madsen and Anita, Mahadevan-Jansen and Jansen, E. Duco and Andreas, Mandelis},
   publisher = {SPIE},
   volume = {8207},
   pages = {82072H},

}

@inproceedings{Otte2012,
   author = {Otte, Christoph and Huttmann, Gereon and Schlaefer, Alexander},
   title = {Feasibiliy of optical detection of soft tissue deformation during needle insertion},
   editor = {David, R. Holmes, III and Kenneth, H. Wong},
   publisher = {SPIE},
   volume = {8316},
   pages = {83160V},
year = { 2012},
url = { https://www.spiedigitallibrary.org/conference-proceedings-of-spie/8316/83160V/Feasibiliy-of-optical-detection-of-soft-tissue-deformation-during-needle/10.1117/12.912538.short}

}

@inproceedings{Franke-2012,
   author = {Franke, Gesa Lilith and Hillmann, Dierck and Claussen, Thorsten and Luhrs, Christian and Koch, Peter and Huttmann, Gereon},
   title = {High resolution holoscopy},
   editor = {Joseph, A. Izatt and James, G. Fujimoto and Valery, V. Tuchin},
   publisher = {SPIE},
   volume = {8213},
   pages = {821324},
URL = { https://doi.org/10.1117/12.911166},
year = { 2012}

}

@inproceedings{Spahr2012,
   author = {Spahr, Hendrik and Rudolph, Linda and Muller, Heike and Birngruber, Reginald and Huttmann, Gereon},
   title = {Imaging of photothermal tissue expansion via phase sensitive optical coherence tomography},
   editor = {Joseph, A. Izatt and James, G. Fujimoto and Valery, V. Tuchin},
   publisher = {SPIE},
   volume = {8213},
   pages = {82131S},
year = { 2012},
url = { https://doi.org/10.1117/12.911429}

}

@inproceedings{Hüttmann2012,
   author = {Hüttmann, G. and Orzekowsky-Schröder, R.},
   title = {Imaging of immune cell dynamics in small intestine and the eye  by 2-photon microcopy},
   booktitle = {7th Workshop on Advanced Multiphoton and Fluorescence Lifetime Imaging Techniques (FLIM 2012)},
year = { 2012},
   abstract = {Autofluorescence based 2-photon microscopy was investigated as a
tool for studying the dynamics of immunological processes in vivo. Nearly
all tissue components were simultaneously visible by autofluorescence and a
nearly complete visualization of tissue architecture was possible. Within
the tissue, immune competent cells like lymphocytes, macrophages and
dendritic cells were visualized in their dynamic interaction with other
cells or surrounding tissues.
Immunological processes were studied in the small intestine and at the
surface of the eye. Excitation and emission spectra of the different mucosal
tissue components were quantitatively determined and a compared to the
respective spectra of endogenous chromophores. It was shown, that by using
only two excitation wavelengths within the tuning range of a Ti:Saphire
laser enterocytes, antigen presenting cells and lysosomes of the small
intestine could be discriminated based on the excitation and emission
properties. By additionally using an intravital nuclear stain, motion of
lymphocytes in the lamina propria and the epithelium of small intestine
villi was quantitatively analyzed. 

2-photon microscopy was also a powerful tool for studying the conjunctiva
and cornea of the eye. Lymphocyte dynamics and uptake of microspheres or
fluorescing heat-inactivated E. coli was followed over time in the
conjunctiva-associated lymphoid tissue of mice. In a different mouse model
of suture induced corneal hem- and lymphangiogenesis, immune cell migration
into lymphatic vessels and luminal transport of individual cells was
observed in vivo.

Autofluorescence based 2-photon intravital microscopy is a valuable tool to
study dynamic immunological processes. While tissue autofluorescence gives a
good overview over all relevant structures and allows for discriminating
different cell types by spectral analysis, the additional combination of
specific staining with external dyes or fluorescent proteins is easily
possible and enhances the potential of the technique further. },

}

@inproceedings{10.1117/12.889669,
author = {Cedric Blatter and Branislav Grajciar and Christoph M. Eigenwillig and Wolfgang Wieser and Benjamin R. Biedermann and Robert Huber and Rainer A. Leitgeb},
title = {{High-speed functional OCT with self-reconstructive Bessel illumination at 1300 nm}},
volume = {8091},
booktitle = {Optical Coherence Tomography and Coherence Techniques V},
editor = {Rainer A. Leitgeb and Brett E. Bouma},
organization = {International Society for Optics and Photonics},
publisher = {SPIE},
pages = {809104},
abstract = {We present a Bessel beam illumination FDOCT setup with FDML buffered swept source at 1300nm. An extended focus
is achieved due to the Bessel beam that preserves its lateral extend over a large depth range. Decoupling the illumination
from the Gaussian detection improves the sensitivity as compared to double passing the ring filter and enables dark field
imaging. Dark field imaging is useful to avoid strong reflexes from the sample's surface that adversely affect the
sensitivity due to the limited dynamic range of high-speed 8bit acquisition cards. Furthermore, Bessel beams exhibit a
self-reconstruction property that allows imaging even behind obstacles such as hairs on skin.
Densely sampled volumes of skin in-vivo with high lateral resolution are acquired at up to 440kHz A-Scan rate. In
addition the possibility of contrasting capillaries with high sensitivity is shown, using inter-B-scan speckle variance
analysis. High-speed imaging is of crucial importance for imaging small details since sample motion artifacts are
reduced and high sampling can be maintained while increasing the B-Scan rate.},
keywords = {Extended focus, Bessel beam, Self-reconstructive illumination, Dark field imaging, Dermatology, Microcirculation imaging, FDML, Swept Source},
year = {2011},
doi = {10.1117/12.889669},
URL = {https://doi.org/10.1117/12.889669}
}

@inproceedings{Klein:11,
author = {Thomas Klein and Wolfgang Wieser and Benjamin R. Biedermann and Christoph M. Eigenwillig and Robert Huber},
booktitle = {CLEO:2011 - Laser Applications to Photonic Applications},
journal = {CLEO:2011 - Laser Applications to Photonic Applications},
keywords = {Optical coherence tomography; Lasers, tunable; Image quality; Imaging techniques; Laser modes; Medical imaging; Mode locking; Optical coherence tomography},
pages = {CWB1},
publisher = {Optica Publishing Group},
title = {FDML laser for megahertz retinal OCT imaging},
year = {2011},
url = {https://opg.optica.org/abstract.cfm?URI=CLEO_SI-2011-CWB1},
doi = {10.1364/CLEO_SI.2011.CWB1},
abstract = {A novel Fourier-domain mode locked (FDML) laser design is presented, yielding the highest wavelength sweep speed reported so far around 1050nm. This enables retinal imaging over a ~70{\textdegree} ultra-wide field of view.},
}

@inproceedings{10.1117/12.875594,
author = {Cedric Blatter and Branislav Grajciar and Robert Huber and Rainer A. Leitgeb},
title = {{Structural and functional imaging with extended focus dark-field OCT at 1300nm}},
volume = {7889},
booktitle = {Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XV},
editor = {James G. Fujimoto and Joseph A. Izatt and Valery V. Tuchin},
organization = {International Society for Optics and Photonics},
publisher = {SPIE},
pages = {78891D},
abstract = {We present an extended focus FDOCT setup with FDML swept source centered at 1310nm. The illumination, preserving
its lateral extend over a large depth range thanks to the use of a Bessel beam, is decoupled from the Gaussian detection in
order to increase the global sensitivity. The efficient spatial separation enables dark-field imaging. In-vivo measurements
in the skin were performed to demonstrate the gain in lateral resolution while preserving the imaging depth. More, the
calculation of the speckle variance between B-Scans allows a clear visualization of the microvasculature.},
keywords = {Extended focus, Dark Field imaging, Bessel beam, FDML Swept Source, dermatology, microvascularisation imaging},
year = {2011},
doi = {10.1117/12.875594},
URL = {https://doi.org/10.1117/12.875594}
}

@inproceedings{Fritz2011,
   author = {Fritz, Andreas and Zegelin, Andrea and Ptaszynski, Lars and Birngruber, Reginald and Brinkmann, Ralf},
   title = {Dynamics of laser induced micro bubble clusters on tissue phantoms},
   volume = {7885},
   pages = {78850S-78850S-6},
   note = {10.1117/12.875031},
   abstract = {Selective retina treatment (SRT) is a laser based method to treat retinal diseases associated with disorders of the retinal pigment epithelium (RPE) while preserving photoreceptors and choroid. Applying microsecond laser pulses to the 100- 200 strongly absorbing melanin granules inside the RPE cells induces transient micro bubbles which disrupt the cells. Aim of this work is to understand bubble dynamics in clusters with respect to the influence of the adjacent retina. Bubble dynamics were investigated in vitro on porcine RPE. An about 200 μm thick layer of agarose gel was applied to the RPE layer in order to simulate the mechanical properties of retina. Different laser pulse durations from 1 ns (532 nm, Nd:YAG) to 1.7 μs (527 nm, Nd:YLF) were used. The bubbles were investigated interferometrically (fiber interferometer @ 830 nm) and with fast flash photography (25 ns flash duration). Bubble lifetimes were measured. The results show that with retina phantoms the bubble formation threshold was reached at 2.5 times higher irradiation than without retina phantom for 1.7 μs laser pulses. The microbubbles generated with 1 ns laser pulses were almost not influenced by the agarose layer. Irradiation twofold over bubble formation threshold resulted in 3.5 times longer bubble lifetimes for μs and 2 times longer for ns pulse durations, respectively.},
   url = {https://www.spiedigitallibrary.org/conference-proceedings-of-spie/7885/1/Dynamics-of-laser-induced-micro-bubble-clusters-on-tissue-phantoms/10.1117/12.875031.short},
   type = {Conference Proceedings},
year = { 2011}
}

@inproceedings{Bonin2011,
   author = {Bonin, Tim and Koch, Peter and Huttmann, Gereon},
   title = {Comparison of fast swept source full-field OCT with conventional scanning OCT},
   editor = {Rainer, A. Leitgeb and Brett, E. Bouma},
   publisher = {SPIE},
   volume = {8091},
   pages = {80911K},
year = { 2011}

}

@inproceedings{Hillmann2011,
   author = {Hillmann, Dierck and Luhrs, Christian  and Bonin, Tim  and Koch, Peter and Vogel, Alfred  and Huttmann, Gereon },
   title = {Holoscopy: holographic optical coherence tomography},
   editor = {Rainer, A. Leitgeb and Brett, E. Bouma},
   publisher = {Proc. SPIE},
   volume = {8091},
   pages = {80911H},
   url = {http://link.aip.org/link/?PSI/8091/80911H/1
http://dx.doi.org/10.1117/12.889485},
   type = {Conference Proceedings},
year = { 2011}
}

@inproceedings{Müller-2011-2,
   author = {Muller, Heike H. and Ptaszynski, Lars and Schlott, Kerstin and Bonin, Tim and Bever, Marco and Koinzer, Stefan and Birngruber, Reginald and Brinkmann, Ralf and Huttmann, Gereon},
   title = {Imaging of temperature distribution and retinal tissue changes during photocoagulation by high speed OCT},
   editor = {James, G. Fujimoto and Joseph, A. Izatt and Valery, V. Tuchin},
   publisher = {SPIE},
   volume = {7889},
   pages = {78890E},
URL = { https://doi.org/10.1117/12.874788},
year = { 2011}

}

@inproceedings{Just2011,
   author = {Just, T. and Pau, H. W. and Lankenau, E. and Huttmann, G.},
   title = {OCT in the field of laryngology: further perspectives},
   editor = {Nikiforos, Kollias and Bernard, Choi and Haishan, Zeng and Hyun Wook, Kang and Bodo, E. Knudsen and Brian, J. Wong and Justus, F. R. Ilgner and Kenton, W. Gregory and Guillermo, J. Tearney and Laura, Marcu and Henry, Hirschberg and Steen, J. Madsen and Andreas, Mandelis and Anita, Mahadevan-Jansen and Jansen, E. Duco},
   publisher = {SPIE},
   volume = {7883},
   pages = {78831W},
Year = { 2011}

}

@inproceedings{Schlott2011,
   author = {Schlott, Kerstin and Koinzer, Stefan and Ptaszynski, Lars and Luft, Susanne and Baade, Alex and Bever, Marco and Roider, Johann and Birngruber, Reginald and Brinkmann, Ralf},
   title = {Optoacoustic temperature determination and automatic coagulation control in rabbits},
   booktitle = {Ophthalmic Technologies XXI },
   editor = {Ho, Fabrice Manns; Per G. Söderberg; Arthur},
   publisher = {Proc. SPIE},
   volume = {7885},
   note = {10.1117/12.875104},
   abstract = {Retinal laser photocoagulation is an established treatment method for many retinal diseases like macula edema or diabetic retinopathy. The selection of the laser parameters is so far based on post treatment evaluation of the lesion size and strength. Due to local pigment variations in the fundus and individual transmission the same laser parameters often lead to an overtreatment. Optoacoustic allows a non invasive monitoring of the retinal temperature increase during retinal laser irradiation by measuring the temperature dependent pressure amplitudes, which are induced by short probe laser pulses. A 75 ns/ 523 nm Nd:YLF was used as a probe laser at a repetition rate of 1 kHz, and a cw / 532 nm treatment laser for heating. A contact lens was modified with a ring-shaped ultrasonic transducer to detect the pressure waves at the cornea. Temperatures were collected for irradiations leading to soft or invisible lesions. Based on this data the threshold for denaturation was found. By analyzing the initial temperature increase, the further temperature development during irradiation could be predicted. An algorithm was found to calculate the irradiation time, which is needed for a soft lesion formation, from the temperature curve. By this it was possible to provide a real-time dosimetry by automatically switching off the treatment laser after the calculated irradiation time. Automatically controlled coagulations appear softer and more uniformly.},
   keywords = {AutoPhoN},
   url = {http://dx.doi.org/10.1117/12.875104},
   type = {Conference Proceedings},
year = { 2011}
}

@inproceedings{Horstmann2011,
   author = {Horstmann, Jens and Baade, Alexander and Brinkmann, Ralf},
   title = {Photoacoustic blood vessel detection during surgical laser interventions},
   publisher = {SPIE ECBO},
   volume = {8092},
   pages = {80920Z-80920Z-6},
   note = {10.1117/12.889635},
   abstract = {This paper presents a discussion about the potential of photoacoustics with regard to its application in surgical assistance during minimally invasive, laser assisted interventions. Aim of the work is the detection of obscured large blood vessels in order to prevent unintentional dissection. Based on spectroscopic investigations of the target tissue (liver), a wavelength for the photoacoustic excitation laser was chosen with respect to a high absorption contrast between the vessel and the surrounding liver tissue. An experimental setup featuring a simple liver model is created. Preliminary results show, that vessels with a diameter of 2 mm can be detected up to a distance of 1 mm from the treatment fibre. It is shown, that detection of acoustic waves induced inside liver is feasible over distances higher than 10 cm.},
   url = {http://dx.doi.org/10.1117/12.889635},
   type = {Conference Proceedings},
year = { 2011}
}

@inproceedings{Bonin2011,
   author = {Bonin, Tim and Hagen-Eggert, Martin and Franke, Gesa and Koch, Peter and Huttmann, Gereon},
   title = {Ultra highspeed in-vivo Fourier domain full-field OCT of the human retina},
   editor = {James, G. Fujimoto and Joseph, A. Izatt and Valery, V. Tuchin},
   publisher = {SPIE},
   volume = {7889},
   pages = {788906},
year = { 2011}

}

@inproceedings{Hagen-Eggert2011,
   author = {Hagen-Eggert, M. and Hillmann, D. and Koch, P. and Huttmann, G.},
   title = {Diffusion-sensitive Fourier-domain optical coherence tomography},
   editor = {James, G. Fujimoto and Joseph, A. Izatt and Valery, V. Tuchin},
   publisher = {SPIE},
   volume = {7889},
   pages = {78892B},

}

@inproceedings{Hüttmann2011,
   author = {Hüttmann, Gereon and Rahmanzadeh, Ramtin and Rudnitzki, Florian and Endl, Elmar and Hasan, Tayyaba},
   title = {Targeted molecular effects through laser-irradiated nanoabsorbers},
   editor = {Newsrrom, SPIE},
   DOI = {10.1117/2.1201102.003548},
   type = {Conference Proceedings},
   year = { 2011}
}

@inproceedings{10.1117/12.854238,
author = {Sebastian Marschall and Thomas Klein and Wolfgang Wieser and Benjamin Biedermann and Kevin Hsu and Bernd Sumpf and Karl-Heinz Hasler and G{\"o}tz Erbert and Ole B. Jensen and Christian Pedersen and Robert Huber and Peter E. Andersen},
title = {{High-power FDML laser for swept source-OCT at 1060 nm}},
volume = {7715},
booktitle = {Biophotonics: Photonic Solutions for Better Health Care II},
editor = {J{\"u}rgen Popp and Wolfgang Drexler and Valery V. Tuchin and Dennis L. Matthews},
organization = {International Society for Optics and Photonics},
publisher = {SPIE},
pages = {77150B},
abstract = {We present a novel frequency-swept light source working at 1060nm that utilizes a tapered amplifier as gain
medium. These devices feature significantly higher saturation power than conventional semiconductor optical
amplifiers and can thus improve the limited output power of swept sources in this wavelength range. We
demonstrate that a tapered amplifier can be integrated into a 
fiber-based swept source and allows for high-speed
FDML operation. The developed light source operates at a sweep rate of 116kHz with an effective average
output power in excess of 30mW. With a total sweep range of 70 nm an axial resolution of 15 μm in air (~11μm
in tissue) for OCT applications can be achieved.},
keywords = {optical coherence tomography, swept source, tunable laser, tapered amplifier, fourier domain mode-locking},
year = {2010},
doi = {10.1117/12.854238},
URL = {https://doi.org/10.1117/12.854238}
}

@inproceedings{10.1117/12.842011,
author = {Sebastian Marschall and Thomas Klein and Wolfgang Wieser and Benjamin Biedermann and Kevin Hsu and Bernd Sumpf and Karl-Heinz Hasler and G{\"o}tz Erbert and Ole B. Jensen and Christian Pedersen and Robert Huber and Peter E. Andersen},
title = {{FDML swept source at 1060 nm using a tapered amplifier}},
volume = {7554},
booktitle = {Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XIV},
editor = {Joseph A. Izatt and James G. Fujimoto and Valery V. Tuchin},
organization = {International Society for Optics and Photonics},
publisher = {SPIE},
pages = {75541H},
abstract = {We present a novel frequency-swept light source working at 1060nm that utilizes a tapered amplifier as gain
medium. These devices feature significantly higher saturation power than conventional semiconductor optical
amplifiers and can thus improve the limited output power of swept sources in this wavelength range. We
demonstrate that a tapered amplifier can be integrated into a fiber-based swept source and allows for high-speed
FDML operation. The developed light source operates at a sweep rate of 116kHz with an effective average
output power in excess of 30mW. With a total sweep range of 70 nm an axial resolution of 15 μm in air (~11μm in tissue) for OCT applications can be achieved.},
keywords = {optical coherence tomography, swept source, tunable laser, tapered amplifier, fourier domain mode-locking},
year = {2010},
doi = {10.1117/12.842011},
URL = {https://doi.org/10.1117/12.842011}
}

@inproceedings{Miura2010,
   author = {Miura, Y and Huettmann, G and Orzekowsky-Schroeder, R and Steven, P and Szaszák, M and Koop, N and Brinkmann, R},
   title = {Appearance of autofluorescence in RPE cells at the rim of photocoagulation},
   booktitle = {FLIM 2010 - Symposium "Fluorescence Lifetime Imaging of the Human Retina"},
   type = {Conference Proceedings},
Year = { 2010}
}

@inproceedings{Just,
   author = {Just, T. and Lankenau, E. and Huttmann, G. and Pau, H. W.},
   title = {An optical coherence tomography study for imaging the round window niche and the promontorium tympani},
   editor = {Nikiforos, Kollias and Bernard, Choi and Haishan, Zeng and Reza, S. Malek and Brian, J. Wong and Justus, F. R. Ilgner and Kenton, W. Gregory and Guillermo, J. Tearney and Laura, Marcu and Henry, Hirschberg and Steen, J. Madsen and Andreas, Mandelis and Anita, Mahadevan-Jansen and Jansen, E. Duco},
   publisher = {SPIE},
   volume = {7548},
   pages = {754833},

}