@inproceedings{Deen2020,
   author = {Deen, A D;Pfeiffer, T;H, van Beusekom.;Essers, J;Huber, R;van der Steen, A.F.W.;van Soest, G and Wang, T},
   title = {Thermo-elastic optical coherence microscopy},
   booktitle = {Proc.SPIE},
   volume = {11252},
abstarct = {The absorption of laser pulses by tissue leads not only to the generation of acoustic waves, but also to nanometer
to sub-micrometer scale displacement. After the initial expansion, a quasi-steady state is achieved in a few
microseconds. Previously we introduced the concept of thermo-elastic optical coherence tomography (TE-OCT)
to \visualise" the rapid thermo-elastic expansion by measuring the Doppler phase shift rather than \listening"
to the acoustic wave as in photoacoustic imaging. In this study, we built a microscopic setup for high-speed
3D TE-OCT imaging, by means of thermo-elastic optical coherence microscopy (TE-OCM). The repetition rate
of pulsed laser was set to 100 Hz and the line rate of the OCT system is 1.5 MHz. The OCT beam and the
laser pulse were focused upon the same location on the sample FWHM spot sizes of 300 m for the pulsed laser
and 40 m FWHM for the OCT beam. For each laser pulse, an M-mode OCT image consisting of 90 A-lines
was acquired. The Doppler phase shift was extracted by comparing the phase signal before and after the pulse
arrival. Within 6 minutes, a 3D TE-OCM image (10 x 10 x 4 mm3) can be acquired and processed. Imaging
experiments were carried out in swine meat using 1210 nm excitation wavelength to highlight lipid in tissue.
The results show that no signicant displacement was detected in swine muscle while strong displacement was
observed in lipid, owing to the optical absorption features. Furthermore, fatty tissue is easily identied in the
3D TE-OCM image while the conventional OCT images provides the structural information.},

   pages = {112520H},
   DOI = {10.1117/12.2550998},
   url = {https://doi.org/10.1117/12.2550998},
   type = {Conference Proceedings}
}

@inproceedings{Deen2020,
   author = {Deen, Aaron Doug;Pfeiffer, Tom;Van Beusekom, Heleen;Essers, Jeroen;Huber, Robert;van der Steen, Antonius FW;Van Soest, Gijs and Wang, Tianshi},
   title = {Thermo-elastic optical coherence microscopy},
   booktitle = {Advanced Chemical Microscopy for Life Science and Translational Medicine},
   publisher = {International Society for Optics and Photonics},
url = { https://www.spiedigitallibrary.org/conference-proceedings-of-spie/11252/112520H/Thermo-elastic-optical-coherence-microscopy/10.1117/12.2550998.short}
   volume = {11252},
   pages = {112520H},
   type = {Conference Proceedings}
}

@inproceedings{10.1117/12.2527123,
author = {Yoko Miura and Wolfgang Draxinger and Christin Grill and Tom Pfeiffer and Salvatore Grisanti and Robert Huber},
title = {{MHz-OCT for low latency virtual reality guided surgery: first wet lab experiments on ex-vivo porcine eye
}},
volume = {11078},
booktitle = {Optical Coherence Imaging Techniques and Imaging in Scattering Media III},
editor = {Maciej Wojtkowski and Stephen A. Boppart and Wang-Yuhl Oh},
organization = {International Society for Optics and Photonics},
publisher = {SPIE},
pages = {110780E},
abstract = {MHz-OCT systems based on FDML swept laser sources combined with the massive parallel processing capabilities of modern computer hardware enable volumetric imaging, processing and stereoscopic display at video rates. The increasing image quality and speed might enable new fields of application where the volumetric OCT completely replaces stereoscopic microscopes instead of being a mere supplement. Aside from the depth resolving capability, a particular advantage is the ability to display a whole image volume from arbitrary points of view without the need to move the actual microscope or to rotate the patient’s eye. Purely digital microscopy is already offered as alternative to traditional through-an-eyepiece surgical microscope. We explore the use of virtual reality to present digital OCT microscopy images to a trained surgeon, carrying out a series of surgical procedures ex-vivo on a porcine eye model.},
keywords = {virtual reality, surgery guidance , real-time OCT, user experience},
year = {2019},
doi = {10.1117/12.2527123},
URL = {https://doi.org/10.1117/12.2527123}
}

@inproceedings{10.1117/12.2526796,
author = {Madita G{\"o}b and Tom Pfeiffer and Robert Huber},
title = {{Towards combined optical coherence tomography and multi-spectral imaging with MHz a-scan rates for endoscopy}},
volume = {11078},
booktitle = {Optical Coherence Imaging Techniques and Imaging in Scattering Media III},
editor = {Maciej Wojtkowski and Stephen A. Boppart and Wang-Yuhl Oh},
organization = {International Society for Optics and Photonics},
publisher = {SPIE},
pages = {110780Y},
abstract = {We demonstrate a preliminary setup of a combined MHz-OCT and RGB narrowband reflection microscope and investigate the performance of the new RGB branch and different display modes of colored OCT data sets.},
keywords = {MHz OCT, multi-spectral imaging, Optical Coherence Tomography, Fourier Domain Mode Locked , FDML, RGB, Color },
year = {2019},
doi = {10.1117/12.2526796},
URL = {https://doi.org/10.1117/12.2526796}
}

@inproceedings{10.1117/12.2527034,
author = {Julian Klee and Jan Philip Kolb and Christin Grill and Wolfgang Draxinger and Tom Pfeiffer and Robert Huber},
title = {{Zero roll-off retinal MHz-OCT using an FDML-laser}},
volume = {11078},
booktitle = {Optical Coherence Imaging Techniques and Imaging in Scattering Media III},
editor = {Maciej Wojtkowski and Stephen A. Boppart and Wang-Yuhl Oh},
organization = {International Society for Optics and Photonics},
publisher = {SPIE},
pages = {110780S},
abstract = {Optical coherence tomography (OCT) applications like ultra-widefield and full eye-length imaging are of high interest for various diagnostic purposes. In swept-source OCT these techniques require a swept light source, which is coherent over the whole imaging depth. We present a zero roll-off 1060 nm Fourier Domain Mode Locked-Laser (FDML-Laser) for retinal OCT imaging at 1.7 MHz A-scan rate and first long-range imaging results with it. Several steps such as improved dispersion compensation and frequency regulation were performed and will be discussed. Besides virtually no loss in OCT signal over the maximum depth range of 4.6 mm and very good dynamic range was observed. Roll-off measurements show no decrease of the point-spread function (PSF), while maintaining a high dynamic range.},
keywords = {optical coherence tomography, OCT, tunable laser, Fourier Domain Mode Locking, FDML, MHz OCT},
year = {2019},
doi = {10.1117/12.2527034},
URL = {https://doi.org/10.1117/12.2527034}
}

@INPROCEEDINGS{8872571,
  author={Weng, Daniel and Hakert, Hubertus and Blömker, Torben and Kolb, Jan Philip and Strauch, Matthias and Eibl, Matthias and Lamminger, Philipp and Karpf, Sebastian and Huber, Robert},
  booktitle={2019 Conference on Lasers and Electro-Optics Europe & European Quantum Electronics Conference (CLEO/Europe-EQEC)}, 
  title={Sub-Nanosecond Pulsed Fiber Laser for 532nm Two-Photon Excitation Fluorescence (TPEF) Microscopy of UV Transitions}, 
  year={2019},
  volume={},
  number={},
  pages={1-1},
  abstract={Summary form only given. Two-photon microscopy is a powerful technique for in vivo imaging, due to its high penetration depth and axial sectioning. Usually excitation wavelengths in the near infrared are used. However, most fluorescence techniques for live cell imaging require labeling with exogenous fluorophores. It has been shown that shorter wavelengths can be used to excite the autofluorescence of endogenous proteins, e.g. tryptophan. Recently we demonstrated a fully fiber-based laser source built around a directly modulated, ytterbium amplified 1064 nm laser diode with sub-nanosecond pulses for two-photon imaging [2]. The overall system enables to capture high-speed fluorescence lifetime imaging (FLIM) with single pulse excitation. Here, we extend the spectral range of this laser source by frequency doubling it to 532nm to achieve two-photon excited fluorescence microscopy (TPM) in the ultraviolett (UV) range to harness endogenous autofluorescence. In this presentation we explore first TPM results of tryptophan to investigate signal levels and fi delity before transitioning to biological tissues. It has been shown that TPM of endogenous tryptophan can be used to visualize immune system activity in vivo. Our laser source could be a cheap, flexible and fiber-based alternative to the OPO-based Ti:Sa Lasers currently employed. The basic concept of our design is to shift the wavelength of the pulsed fiber-based master oscillator power amplifier (MOPA) by second-harmonic generation (SHG) using phase-matching in a KTP crystal. This generates a coherent output at 532nm at a maximal peak power of 500W. We achieved a maximum conversion efficiency of about 17%. After the SHG module, the 532nm light is coupled into a single-mode fiber and delivered to a home built microscope. A 40x microscope objective is used to excite the sample and epi-collect the fluorescence. The fluorescence is recorded on a UV-enhanced photomultiplier tube (PMT). For a proof of concept measurement, crystalized tryptophan was imaged. Here we show signals of pure tryptophan, with laser parameters of 1MHz repetition rate and 100ps pulse duration. We used spectral bandpass fi lters in order to detect only fluorescence signal, however, from crystalized tryptophan we observed an unexpected short lifetime. We have recently shown that we can shift our laser output from 1064nm to longer wavelengths. By shifting to 1180nm and frequency doubling to 590nm a more efficient fluorescence excitation of tryptophan can be achieved. In the future we aim at in vivo imaging with our setup.},
  keywords={},
  doi={10.1109/CLEOE-EQEC.2019.8872571},
  ISSN={},
  month={June}}

@inproceedings{10.1117/12.2507866,
author = {Jan Philip Kolb and Daniel Weng and Hubertus Hakert and Matthias Eibl and Wolfgang Draxinger and Tobias Meyer and Thomas Gottschall and Ralf  Brinkmann and Reginald Birngruber and J{\"u}rgen Popp and Jens Limpert and Sebastian Nino Karpf and Robert Huber},
title = {{Virtual HE histology by fiber-based picosecond two-photon microscopy}},
volume = {10882},
booktitle = {Multiphoton Microscopy in the Biomedical Sciences XIX},
editor = {Ammasi Periasamy and Peter T. C. So and Karsten K{\"o}nig},
organization = {International Society for Optics and Photonics},
publisher = {SPIE},
pages = {108822F},
abstract = {Two-Photon Microscopy (TPM) can provide three-dimensional morphological and functional contrast in vivo. Through proper staining, TPM can be utilized to create virtual, HE equivalent images and thus can improve throughput in histology-based applications. We previously reported on a new light source for TPM that employs a compact and robust fiber-amplified, directly modulated laser. This laser is pulse-to-pulse wavelength switchable between 1064 nm, 1122 nm, and 1186 nm with an adjustable pulse duration from 50ps to 5ns and arbitrary repetition rates up to 1MHz at kW-peak powers. Despite the longer pulse duration, it can achieve similar average signal levels compared to fs-setups by lowering the repetition rate to achieve similar cw and peak power levels. The longer pulses lead to a larger number of photons per pulse, which yields single shot fluorescence lifetime measurements (FLIM) by applying a fast 4 GSamples/s digitizer. In the previous setup, the wavelengths were limited to 1064 nm and longer. Here, we use four wave mixing in a non-linear photonic crystal fiber to expand the wavelength range down to 940 nm. This wavelength is highly suitable for imaging green fluorescent proteins in neurosciences and stains such as acridine orange (AO), eosin yellow (EY) and sulforhodamine 101 (SR101) used for histology applications. In a more compact setup, we also show virtual HE histological imaging using a direct 1030 nm fiber MOPA.},
keywords = {Multiphoton Microscopy, Four Wave Mixing, FWM, Histology, Laser, Non Linear Microscopy, Two Photon Microscopy, JenLab Young Investigator Award},
year = {2019},
doi = {10.1117/12.2507866},
URL = {https://doi.org/10.1117/12.2507866}
}

@inproceedings{Muenter2019,
title = {4D microscopic optical coherence tomography imaging of ex vivo mucus transport},
author = { M\"{u}nter, M; Schulz-Hildebrandt, H; Pieper, M; K\"{o}nig, P and  H\"{u}ttmann, G},
url = {https://www.spiedigitallibrary.org/conference-proceedings-of-spie/11078/2527138/4D-microscopic-optical-coherence-tomography-imaging-of-ex-vivo-mucus/10.1117/12.2527138.full},

isbn = {9781510628496},
year = {2019},
date = {2019-01-01},
booktitle = {Proc. SPIE 11078, Optical Coherence Imaging Techniques and Imaging in Scattering Media III},
volume = {11078},
number = {11},
pages = {1--5},
keywords = {OCM},
pubstate = {published},
tppubtype = {inproceedings}
}

@inproceedings{Ahrens2019,
title = {An endomicroscopic OCT for clinical trials in the field of ENT (Invited)},
author = { Ahrens, M; Idel, C; Chaker, A; Wollenberg, B; K\"{o}nig, P; Schulz-Hildebrandt, H and H\"{u}ttmann, G},
url = {https://www.spiedigitallibrary.org/conference-proceedings-of-spie/11073/2527099/An-endomicroscopic-OCT-for-clinical-trials-in-the-field-of/10.1117/12.2527099.full},

isbn = {9781510628397},
year = {2019},
date = {2019-01-01},
booktitle = {Proc. SPIE 11073, Clinical and Preclinical Optical Diagnostics II},
number = {110730U},
pages = {1--4},
keywords = {Endoskope, meos, OCM},
pubstate = {published},
tppubtype = {inproceedings}
}

@inproceedings{schmidt2019coexistence,
  title={Coexistence of Intensity Pattern Types in Broadband Fourier Domain Mode Locked (FDML) Lasers},
  author={Schmidt, M; Pfeiffer, T; Grill, C; Huber, R and Jirauschek, C},
  booktitle={2019 Conference on Lasers and Electro-Optics Europe \& European Quantum Electronics Conference (CLEO/Europe-EQEC)},
  pages={1--1},
  year={2019},
  organization={IEEE},
keywords= { AG-Huber_FDML},
url={  https://ieeexplore.ieee.org/document/8872381}

}

@inproceedings{Bliedtner2019,
   author = {Bliedtner,K; Seifert, E and Brinkmann,R},
   title = {Dosimetry for microsecond selective laser trabeculoplasty},
   volume = {11079},
   DOI = {10.1117/12.2526987},
   year = {2019},
keywords = {Ophthalmology, ophthalmic optics and devices, selective laser trabeculoplasty, micro bubble detection},
booktitle =    {Proc. SPIE 11079, Medical Laser Applications
and Laser-Tissue Interactions IX},
   type = {Conference proceedings}
}

@inproceedings{Strenge2019,
Title = {Ex vivo and in vivo imaging of human brain tissue with different OCT systems},
author = {Strenge, P.; Lange, B; Grill, C; Draxinger, W; Dannicke, V; Theisen-Kunde, D; Bonsanto, M; Huber, R and Brinkmann, R},
abstract = {Optical coherence tomography (OCT) is a non-invasive imaging technique which is currently investigated for intraoperative detection of residual tumor during resection of human gliomas. Three different OCT systems were used for imaging of human glioblastoma in vivo (830nm spectral domain (SD) OCT integrated into a surgical microscope) and ex vivo (940nm SD-OCT and 1310nm swept-source MHz-OCT using a Fourier domain mode locked (FDML) laser). Before clinical data acquisition, the systems were characterized using a three-dimensional point-spread function phantom. To distinguish tumor from healthy brain tissue later on, attenuation coefficients of each pixel in OCT depth profiles are calculated. First examples from a clinical study show that the pixel-resolved calculation of the attenuation coefficient provides a good image contrast and confirm that white matter shows a higher signal and more homogeneous signal structure than tumorous tissue.},
keywords = {Optical coherence tomography, OCT, FDML laser, MHz-OCT, glioblastoma, intraoperative imaging, brain
imaging},
   DOI= {10.1117/12.2526932},
   year = {2019},
   type = {Conference Paper}
}

@inproceedings{Haak2019,
author = {Haak, Rainer and Ahrens, Martin and Schneider, Hartmut and Strumpski, Michaela and Rueger, Claudia and Haefer, Matthias and H{\"{u}}ttmann, Gereon and Theisen-Kunde, Dirk and Schulz-Hildebrandt, Hinnerk},
booktitle = {Proc. SPIE 11073, Clinical and Preclinical Optical Diagnostics II},
doi = {10.1117/12.2527185},
isbn = {9781510628397},
number = {110730W},
pages = {1--4},
title = {{Handheld OCT probe for intraoral diagnosis on teeth}},
keywords = {OCT,Endoskope},
year = {2019},
}

@inproceedings{Detrez2019,
   author = {Detrez, N;Miura, Y;Seifert, E;Theisen-Kunde, D and Brinkmann, R},
   title = {Heating and optoacoustic temperature determination of cell cultures},
   publisher = {SPIE},
   volume = {11079},
   series = {European Conferences on Biomedical Optics},
booktitle =    {Proc. SPIE 11079, Medical Laser Applications
and Laser-Tissue Interactions IX},
   url = {https://doi.org/10.1117/12.2527024},
keywords = {Laser, Noninvasive thermometry, hyperthermia, temperature measurement, photoacoustics}, optoacoustics,
   year = {2019},
   type = {Conference Proceeding}
}

@inproceedings{Kastner:19,
author = {Kastner, D; Bl\"{o}mker, T; Pfeiffer, T; Grill, C; Schmidt, M; Jirauschek, C and Huber, R},
booktitle = {2019 Conference on Lasers and Electro-Optics Europe and European Quantum Electronics Conference},
journal = {2019 Conference on Lasers and Electro-Optics Europe and European Quantum Electronics Conference},
keywords = {Fourier domain mode locking; Image quality; Optical coherence tomography; Phase noise; Ring lasers; Tunable lasers},
pages = {cj_7_5},
publisher = {Optical Society of America},
title = {Measurement of Inter-Sweep Phase Stability of an FDML Laser with a 10 kHz Tunable Ring Laser},
year = {2019},
keywords = {AG-Huber_FDML, AG-Huber_OCT},
doi = { 10.1109/CLEOE-EQEC.2019.8872860},
abstract = {Fourier Domain Mode Locking (FDML) lasers are light sources that generate a sequence of narrowband optical frequency sweeps at the fundamental or harmonic of the cavity repetition rate \[1\]. This frequency swept output can also be considered as a sequence of strongly chirped, long pulses. FDML lasers are mainly used in swept source optical coherence tomography (SS-OCT), a medical imaging technique. The coherence length of the source, i.e. the intra-sweep phase stability of an FDML sweep, is decisive for the image quality and performance of OCT imaging \[2\].},
}

@InProceedings{Strauch2019,
  author    = {Strauch, Matthias and Kolb, Jan Philip and Weng, Daniel and Wacker, Melanie and Draxinger, Wolfgang and Karpf, Sebastian and Huber, Robert},
  booktitle = {31st Congress of the ESP},
  title     = {Sectioning-Free Virtual H&E Imaging of Tissue Samples with Two-Photon Microscopy},
  year      = {2019},
  keywords  = {AG-Huber_NL},
}

@inproceedings{Schulz-Hildebrandt2019,
author = {Schulz-Hildebrandt, Hinnerk and Meyer-Schell, Naja and Casper, Malte and Evers, Michael and Birngruber, Reginald and Manstein, Dieter and H{\"{u}}ttmann, Gereon},
booktitle = {Proc. SPIE 11073, Clinical and Preclinical Optical Diagnostics II},
doi = {10.1117/12.2527087},
isbn = {9781510628397},
number = {110730L},
pages = {1--3},
title = {{Monitoring temperature induced phase changes in subcutaneous fatty tissue using an astigmatism corrected dynamic needle probe}},
keywords = {OCT, Endoskope},
year = { 2019}
}

@inproceedings{Schulz-Hildebrandt2018a,
title = {Coherence and diffraction limited resolution in microscopic OCT by a unified approach for the correction of dispersion and aberrations},
author = {Schulz-Hildebrandt,H; M\"{u}nter, M; Ahrens,M; Spahr, H; Hillmann, D; K\"{o}nig, P and  H\"{u}ttmann, G},
doi = {10.1117/12.2303755},
isbn = {9781510616745},
year = {2018},
date = {2018-03-05},
booktitle = {2nd Canterbury Conference on OCT with Emphasis on Broadband Optical Sources},
volume = {10591},
pages = {105910O},
abstract = {Optical coherence tomography (OCT) images scattering tissues with 5 to 15 μm resolution. This is usually not sufficient for a distinction of cellular and subcellular structures. Increasing axial and lateral resolution and compensation of artifacts caused by dispersion and aberrations is required to achieve cellular and subcellular resolution. This includes defocus which limit the usable depth of field at high lateral resolution. OCT gives access the phase of the scattered light and hence correction of dispersion and aberrations is possible by numerical algorithms. Here we present a unified dispersion/aberration correction which is based on a polynomial parameterization of the phase error and an optimization of the image quality using Shannon’s entropy. For validation, a supercontinuum light sources and a costume-made spectrometer with 400 nm bandwidth were combined with a high NA microscope objective in a setup for tissue and small animal imaging. Using this setup and computation corrections, volumetric imaging at 1.5 μm resolution is possible. Cellular and near cellular resolution is demonstrated in porcine cornea and the drosophila larva, when computational correction of dispersion and aberrations is used. Due to the excellent correction of the used microscope objective, defocus was the main contribution to the aberrations. In addition, higher aberrations caused by the sample itself were successfully corrected. Dispersion and aberrations are closely related artifacts in microscopic OCT imaging. Hence they can be corrected in the same way by optimization of the image quality. This way microscopic resolution is easily achieved in OCT imaging of static biological tissues.},
keywords = {OCM},
pubstate = {published},
tppubtype = {inproceedings}
}

@inproceedings{Smits2018,
title = {Development and Experimental Validation of a Combined FBG Force and OCT Distance Sensing Needle for Robot-Assisted Retinal Vein Cannulation},
author = {Smits, J; Ourak, M; Gijbels, A;  Esteveny, L; Borghesan, G; Schoevaerdts, L; Willekens; Stalmans, P; Lankenau, E; Schulz-Hildebrandt, H; H\"{u}ttmann, G; Reynaerts, D and  Vander Poorten, E.B},

doi = {10.1109/ICRA.2018.8460983},
year = {2018},
date = {2018-09-20},
journal = {2018 IEEE Intern Conf Robot a Automation (ICRA)},
pages = {129-134},
abstract = {Retinal Vein Occlusion is a common retinal vascular disorder which can cause severe loss of vision. Retinal vein cannulation followed by injection of an anti-coagulant into the affected vein is a promising treatment. However, given the scale and fragility of the surgical workfield, this procedure is considered too high-risk to perform manually. A first successful robot-assisted procedure has been demonstrated. Even though successful, the procedure remains extremely challenging. This paper aims at providing a solution for the limited perception of instrument-tissue interaction forces as well as depth estimation during retinal vein cannulation. The development of a novel combined force and distance sensing cannulation needle relying on Fiber Bragg grating (FBG) and Optical Coherence Tomography (OCT) A-scan technology is reported. The design, the manufacturing process, the calibration method, and the experimental characterization of the produced sensor are discussed. 
The functionality of the combined sensing modalities and the real-time distance estimation algorithm are validated respectively on in-vitro and ex-vivo models.},
keywords = {Endoskope},
pubstate = {published},
tppubtype = {inproceedings}
}

@inproceedings{Cecchetti2019,
   author = {Cecchetti, Leonardo;Wang, Tianshi;Pfeiffer, Tom;Wieser, Wolfgang;van der Steen, Antonius FW;Huber, Robert;van Soest, Gijs and Huber, Robert Alexander},
   title = {Heartbeat optical coherence tomography enables accurate in vivo stents imaging: a quantitative image processing study (Conference Presentation)},
   booktitle = {Diagnostic and Therapeutic Applications of Light in Cardiology 2019},
   publisher = {International Society for Optics and Photonics},
   volume = {10855},
   pages = {1085506},
   type = {Conference Proceedings}
}

@inproceedings{Hakert2019,
   author = {Hakert, Hubertus;Eibl, Matthias;Karpf, Sebastian;Wollenberg, Barbara;Pries, Ralph and Huber, Robert},
   title = {Label-free imaging of tumorous tissue in the Raman fingerprint region with time-encoded (TICO) stimulated Raman scattering (Conference Presentation)},
   booktitle = {Multiphoton Microscopy in the Biomedical Sciences XIX},
   publisher = {International Society for Optics and Photonics},
   volume = {10882},
   pages = {108821R},
   type = {Conference Proceedings}
}

@inproceedings{Wang2019-3,
   author = {Wang, Tianshi;Pfeiffer, Tom;Daemen, Joost;Mastik, Frits;Wieser, Wolfgang;van der Steen, AFW;Huber, Robert and van Soest, Gijs},
   title = {Megahertz intravascular Doppler optical coherence tomography enables simultaneous morphological and flow pattern imaging},
   booktitle = {Diagnostic and Therapeutic Applications of Light in Cardiology 2019},
   publisher = {International Society for Optics and Photonics},
   volume = {10855},
   pages = {1085503},
   type = {Conference Proceedings}
}

@inproceedings{Wang2019-1,
   author = {Wang, Tianshi;Pfeiffer, Tom;Wieser, Wolfgang;van Beusekom, Heleen;Draxinger, Wolfgang;van der Steen, Antonius FW;Huber, Robert and van Soest, Gijs},
   title = {Thermo-elastic optical coherence tomography},
   booktitle = {Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXIII},
   publisher = {International Society for Optics and Photonics},
   volume = {10867},
   pages = {108672C},
   type = {Conference Proceedings}
}

@inproceedings{Vogel2018,
   author = {Uzunbajakava, N E; Varghese, B; Botchkareva, N V; Verhagen, R and Vogel, A},
   title = {Highlighting the nuances behind interaction of picosecond pulses with human skin: Relating distinct laser-tissue interactions to their potential in cutaneous interventions},
   booktitle = {Progress in Biomedical Optics and Imaging - Proceedings of SPIE},
   volume = {10492} ,
   DOI = {10.1117/12.2307804},
   year = {2018},
date = {2018-20-02},
   type = {Conference Proceedings},
year = { 2018}
}

@article{Wang:17,
author = {Tianshi Wang and Tom Pfeiffer and Min Wu and Wolfgang Wieser and Gaetano Amenta and Wolfgang Draxinger and Antonius F. W. van der Steen and Robert Huber and Gijs van Soest},
journal = {Opt. Lett.},
keywords = {Imaging systems; Medical and biological imaging; Optical coherence tomography; Lasers, pulsed ; Fourier domain mode locking; Functional imaging; Laser beams; Nanosecond pulses; Optical coherence tomography; Phantom studies},
number = {17},
pages = {3466--3469},
publisher = {Optica Publishing Group},
title = {Thermo-elastic optical coherence tomography},
volume = {42},
month = {Sep},
year = {2017},
url = {https://opg.optica.org/ol/abstract.cfm?URI=ol-42-17-3466},
doi = {10.1364/OL.42.003466},
abstract = {The absorption of nanosecond laser pulses induces rapid thermo-elastic deformation in tissue. A sub-micrometer scale displacement occurs within a few microseconds after the pulse arrival. In this Letter, we investigate the laser-induced thermo-elastic deformation using a 1.5 MHz phase-sensitive optical coherence tomography (OCT) system. A displacement image can be reconstructed, which enables a new modality of phase-sensitive OCT, called thermo-elastic OCT. An analysis of the results shows that the optical absorption is a dominating factor for the displacement. Thermo-elastic OCT is capable of visualizing inclusions that do not appear on the structural OCT image, providing additional tissue type information.},
}