@article{Fu:24,
author = {Lei Fu and Jing Wang and Siqi Wang and Zhenxi Zhang and Alfred Vogel and Xiao-xuan Liang and Cuiping Yao},
journal = {Opt. Express},
keywords = {Laser beams; Laser light; Laser materials; Laser surgery; Numerical simulation; Phase shift},
number = {6},
pages = {9747--9766},
publisher = {Optica Publishing Group},
title = {Secondary cavitation bubble dynamics during laser-induced bubble formation in a small container},
volume = {32},
month = {Mar},
year = {2024},
url = {https://opg.optica.org/oe/abstract.cfm?URI=oe-32-6-9747},
doi = {10.1364/OE.516264},
abstract = {We investigated secondary cavitation bubble dynamics during laser-induced bubble formation in a small container with a partially confined free surface and elastic thin walls. We employed high-speed photography to record the dynamics of sub-mm-sized laser-induced bubbles and small secondary bubble clouds. Simultaneous light scattering and acoustic measurements were used to detect the oscillation times of laser-induced bubbles. We observed that the appearance of secondary bubbles coincides with a prolonged collapse phase and with re-oscillations of the laser-induced bubble. We observed an asymmetric distribution of secondary bubbles with a preference for the upstream side of the focus, an absence of secondary bubbles in the immediate vicinity of the laser focus, and a migration of laser-induced bubble toward secondary bubbles at large pulse energies. We found that secondary bubbles are created through heating of impurities to form initial nanobubble nuclei, which are further expanded by rarefaction waves. The rarefaction waves originate from the vibration of the elastic thin walls, which are excited either directly by laser-induced bubble or by bubble-excited liquid-mass oscillations. The oscillation period of thin walls and liquid-mass were Twall\&\#x2009;\&\#x003D;\&\#x2009;116 \&\#x00B5;s and Tlm \&\#x2248; 160 \&\#x00B5;s, respectively. While the amplitude of the wall vibrations increases monotonically with the size of laser-induced bubbles, the amplitude of liquid-mass oscillation undulates with increasing bubble size. This can be attributed to a phase shift between the laser-induced bubble oscillation and the liquid-mass oscillator. Mutual interactions between the laser-induced bubble and secondary bubbles reveal a fast-changing pressure gradient in the liquid. Our study provides a better understanding of laser-induced bubble dynamics in a partially confined environment, which is of practical importance for microfluidics and intraluminal laser surgery.},
}

@article{FU2023106664,
title = {Laser induced spherical bubble dynamics in partially confined geometry with acoustic feedback from container walls},
journal = {Ultrasonics Sonochemistry},
volume = {101},
pages = {106664},
year = {2023},
issn = {1350-4177},
doi = {https://doi.org/10.1016/j.ultsonch.2023.106664},
url = {https://www.sciencedirect.com/science/article/pii/S1350417723003760},
author = {Lei Fu and Xiao-Xuan Liang and Sijia Wang and Siqi Wang and Ping Wang and Zhenxi Zhang and Jing Wang and Alfred Vogel and Cuiping Yao},
keywords = {Laser-induced cavitation, Partial confinement, Acoustic feedback, Elastic wall, Vibrations, Extended Rayleigh-Plesset model},
abstract = {We investigated laser-induced cavitation dynamics in a small container with elastic thin walls and free or partially confined surface both experimentally and by numerical investigations. The cuvette was only 8–25 times larger than the bubble in its center. The liquid surface was either free, or two thirds were confined by a piston-shaped pressure transducer. Different degrees of confinement were realized by filling the liquid up to the transducer surface or to the top of the cuvette. For reference, some experiments were performed in free liquid. We recorded the bubble dynamics simultaneously by high-speed photography, acoustic measurements, and detection of probe beam scattering. Simultaneous single-shot recording of radius-time curves and oscillation times enabled to perform detailed investigations of the bubble dynamics as a function of bubble size, acoustic feedback from the elastic walls, and degree of surface confinement. The bubble dynamics was numerically simulated using a Rayleigh-Plesset model extended by terms describing the acoustically mediated feedback from the bubble’s environment. Bubble oscillations were approximately spherical as long as no secondary cavitation by tensile stress occurred. Bubble expansion was always similar to the dynamics in free liquid, and the environment influenced mainly the collapse phase and subsequent oscillations. For large bubbles, strong confinement led to a slight reduction of maximum bubble size and to a pronounced reduction of the oscillation time, and both effects increased with bubble size. The joint action of breakdown-induced shock wave and bubble expansion excites cuvette wall vibrations, which produce alternating pressure waves that are focused onto the bubble. This results in a prolongation of the collapse phase and an enlargement of the second oscillation, or in time-delayed re-oscillations. The details of the bubble dynamics depend in a complex manner on the degree of surface confinement and on bubble size. Numerical simulations of the first bubble oscillation agreed well with experimental data. They suggest that the alternating rarefaction/compression waves from breakdown-induced wall vibrations cause a prolongation of the first oscillation. By contrast, liquid mass movement in the cuvette corners result in wall vibrations causing late re-oscillations. The strong and rich interaction between the bubble and its surroundings may be relevant for a variety of applications such as intraluminal laser surgery and laser-induced cavitation in microfluidics.}
}

@inbook{doi:https://doi.org/10.1002/9783527823550.ch8,
author = {Yao, Cuiping and Liang, Xiao-Xuan and Wang, Sijia and Xin, Jing and Zhang, Luwei and Zhang, Zhenxi},
publisher = {John Wiley & Sons, Ltd},
isbn = {9783527823550},
title = {Optical Theranostics Based on Gold Nanoparticles},
booktitle = {Biomedical Photonic Technologies},
chapter = {8},
pages = {245-284},
doi = {https://doi.org/10.1002/9783527823550.ch8},
url = {https://onlinelibrary.wiley.com/doi/abs/10.1002/9783527823550.ch8},
eprint = {https://onlinelibrary.wiley.com/doi/pdf/10.1002/9783527823550.ch8},
year = {2023},
keywords = {localized surface plasmon resonance, thermo-plasmonic effect, optical imaging, molecular diagnosis, tumor treatment, precise manipulation},
abstract = {Summary To obtain more detailed images of cellular processes or other nanoscale information in the fields of biology and medicine, or to improve phototherapy of cancer, various nanoparticles have emerged as optical probes, contrast agents, or optical absorbing agents. Among different nanoparticles, gold nanoparticle has obtained great attention and application in biomedical fields, such as optoporation, photo imaging, photodiagnosis, and phototherapy, due to their unique tunable optical, surface plasmon resonance, and photothermal features. In this chapter, the general physical mechanism of thermoplasmonic effects of gold nanoparticles was introduced, and the gold nanoparticles enhanced optical imaging, detection, and phototherapy of tumors was summarized.}
}

@article{Yao2017,
   author = {Yao, C; Rudnitzki, F; Hüttmann, G; Zhang, Zand Rahmanzadeh, R},
   title = {Important factors for cell-membrane permeabilization by gold nanoparticles activated by nanosecond-laser irradiation},
journal = {International Journal of Nanomedicine},
  
   pages = {5659-5672},
   DOI = {10.2147/IJN.S140620},
   year = {2017},
   type = {Journal Article}
}

@article{Yao,
   author = {Yao, C and Qu, X. and Zhang, Z. and B., Yao and Hüttmann, G and Rahmanzadeh, R.},
   title = {Influence of Laser Parameters on Membrane Permeability with Nanoparticles and Targeted Antibody Transfection},
   journal = {J Biomed Opt},
   volume = {14},
   pages = {054034},
   note = {Journal article},
   year = {2009}
}

@article{Yao,
   author = {Yao, C. P. and Zhang, Z. X. and Rahmanzadeh, R. and Huettmann, G.},
   title = {Laser-based gene transfection and gene therapy},
   journal = {IEEE Trans Nanobioscience},
   volume = {7},
   number = {2},
   pages = {111-9},
   note = {Yao, C P
Zhang, Z X
Rahmanzadeh, R
Huettmann, G
Research Support, Non-U.S. Gov't
Review
United States
IEEE Trans Nanobioscience. 2008 Jun;7(2):111-9.},
   abstract = {The plasma membrane of mammalian cells can be transiently permeablized by optical means and exogenous materials or genes can be introduced into the cytoplasm of living cells. Until now, few mechanisms were exploited for the manipulation: laser is directly and tightly focused on the cells for optoinjection, laser-induced stress waves, photochemical internalization, and irradiation of selective cell targeting with light-absorbing particles. During the past few years, extensive progress and numerous breakthroughs have been made in this area of research. This review covers four different laser-assisted transfection techniques and their advantages and disadvantages. Universality towards various cell lines is possibly the main advantage of laser-assisted optoporation in comparison with presently existing methods of cell transfection.},
   keywords = {Cell Membrane/ radiation effects
DNA/ administration & dosage/ pharmacokinetics
Gene Therapy/ methods
Lasers
Transfection/ methods},
   year = {2008}
}

@article{Yao,
   author = {Yao, C. and Rahmanzadeh, R. and Endl, E. and Zhang, Z. and Gerdes, J. and Huttmann, G.},
   title = {Elevation of plasma membrane permeability by laser irradiation of selectively bound nanoparticles},
   journal = {J Biomed Opt},
   volume = {10},
   number = {6},
   pages = {064012},
   note = {Yao, Cuiping
Rahmanzadeh, Ramtin
Endl, Elmar
Zhang, Zhenxi
Gerdes, Johannes
Huttmann, Gereon
Research Support, Non-U.S. Gov't
United States
J Biomed Opt. 2005 Nov-Dec;10(6):064012.},
   abstract = {Irradiation of nanoabsorbers with pico- and nanosecond laser pulses could result in thermal effects with a spatial confinement of less than 50 nm. Therefore absorbing nanoparticles could be used to create controlled cellular effects. We describe a combination of laser irradiation with nanoparticles, which changes the plasma membrane permeability. We demonstrate that the system enables molecules to penetrate impermeable cell membranes. Laser light at 532 nm is used to irradiate conjugates of colloidal gold, which are delivered by antibodies to the plasma membrane of the Hodgkin's disease cell line L428 and/or the human large-cell anaplastic lymphoma cell line Karpas 299. After irradiation, membrane permeability is evaluated by fluorescence microscopy and flow cytometry using propidium iodide (PI) and fluorescein isothiocyanate (FITC) dextran. The fraction of transiently permeabilized and then resealed cells is affected by the laser parameter, the gold concentration, and the membrane protein of the different cell lines to which the nanoparticles are bound. Furthermore, a dependence on particle size is found for these interactions in the different cell lines. The results suggest that after optimization, this method could be used for gene transfection and gene therapy.},
   keywords = {Biopolymers/pharmacokinetics
Cell Line, Tumor
Cell Membrane Permeability/ physiology/ radiation effects
Drug Delivery Systems/ methods
Fluoresceins/ pharmacokinetics
Humans
Lasers
Lymphoma/ metabolism
Nanostructures},
   year = {2005}
}

@article{Hüttmann2005,
   author = {Hüttmann, Gereon and Yao, Cuiping and Endl, Elmar},
   title = {New concepts in laser medicine: Towards a laser surgery with cellular precision},
   journal = {Medical laser application},
   volume = {20},
   number = {2},
   pages = {135-139},
   abstract = {New concepts and instrumentation in laser medicine are driven by the progress in optical technology as well as by advances in the understanding of the interaction of optical irradiation with tissue, especially at a macromolecular scale, and by the changing needs in health care. Complexity and costs of laser sources will decrease due to the use of semiconductor and fiber lasers, and complex or non-linear mechanisms by which the radiation effects tissues are better understood, especially when ultra-short laser pulses are used. Especially femtosecond lasers and nanotechnology have the potential to treat diseases at a cellular level. Focused femtosecond irradiation was successfully used to manipulate tissues with subcellular precision. Laser-irradiated nanoparticles can selectively destroy individual cells.},
   keywords = {Mikro- und Nanowirkungen
Selective Foto thermolyse
Faserlaser
Femtosekundenlaser
Nanopartikel
Micro- and nanoeffects
Selective photothermolysis
Fiber laser
Femtosecond laser
Nanoparticles},
   year = {2005}
}