Claus
von der Burchard,
Helge
Sudkamp,
Jan
Tode,
Christoph
Ehlken,
K.
Purtskhvanidze,
Moritz
Moltmann,
B.
Heimes,
Peter
Koch,
Michael
Münst,
Malte
vom Endt,
Timo
Kepp,
Dirk
Theisen-Kunde,
Inke R.
König,
Gereon
Hüttmann, and
Johann
Roider,
Self-Examination Low-Cost Full-Field Optical Coherence Tomography (SELFF-OCT) for neovascular age-related macular degeneration: a cross-sectional diagnostic accuracy study, BMJ Open , vol. 12, no. 6, pp. e055082, 2022.
Self-Examination Low-Cost Full-Field Optical Coherence Tomography (SELFF-OCT) for neovascular age-related macular degeneration: a cross-sectional diagnostic accuracy study, BMJ Open , vol. 12, no. 6, pp. e055082, 2022.
DOI: | 10.1136/bmjopen-2021-055082 |
Datei: | e055082.abstract |
Bibtex: | ![]() @article{von-der-Burchardt2022, author = {von der Burchard, C;Sudkamp, H;Tode, J;Ehlken, C;Purtskhvanidze, K;Moltmann, M;Heimes, B;Koch, P;Münst, M;vom Endt, M;Kepp, T;Theisen-Kunde, D;König, I;Hüttmann, G and Roider, J}, title = {Self-Examination Low-Cost Full-Field Optical Coherence Tomography (SELFF-OCT) for neovascular age-related macular degeneration: a cross-sectional diagnostic accuracy study}, journal = {BMJ Open}, volume = {12}, number = {6}, pages = {e055082}, DOI = {10.1136/bmjopen-2021-055082}, url = {http://bmjopen.bmj.com/content/12/6/e055082.abstract}, year = {2022}, type = {Journal Article} } |
Michel
Wunderlich,
Peter
Koch,
Helge
Sudkamp,
Michael
Münst,
Malte
Endt,
Moritz
Moltmann, and
Gereon
Hüttmann,
Eye tracking with off-axis full-field OCT by local analysis of recorded interferograms, in Ophthalmic Technologies XXXI , Daniel X. Hammer and Karen M. Joos and Daniel V. Palanker, Eds. SPIE, 2021. pp. 116231Q.
Eye tracking with off-axis full-field OCT by local analysis of recorded interferograms, in Ophthalmic Technologies XXXI , Daniel X. Hammer and Karen M. Joos and Daniel V. Palanker, Eds. SPIE, 2021. pp. 116231Q.
DOI: | 10.1117/12.2583030 |
Datei: | 12.2583030 |
Bibtex: | ![]() @inproceedings{10.1117/12.2583030, author = {Michel Wunderlich and Peter Koch and Helge Sudkamp and Michael M{\"u}nst and Malte vom Endt and Moritz Moltmann and Gereon H{\"u}ttmann}, title = {{Eye tracking with off-axis full-field OCT by local analysis of recorded interferograms}}, volume = {11623}, booktitle = {Ophthalmic Technologies XXXI}, editor = {Daniel X. Hammer and Karen M. Joos and Daniel V. Palanker}, organization = {International Society for Optics and Photonics}, publisher = {SPIE}, pages = {116231Q}, keywords = {Retinal motion tracking in Off-Axis Full-Field OCT by local analy, Michel Wunderlich, Medizinsches Laserzentrum Lübeck, motion tracking, eye tracking, off-axis full-field time-domain OCT, OCT, retina}, year = {2021}, doi = {10.1117/12.2583030}, URL = {https://doi.org/10.1117/12.2583030} } |
Claus
von der Burchard,
Moritz
Moltmann,
Jan
Tode,
Christoph
Ehlken,
Helge
Sudkamp,
Dirk
Theisen-Kunde,
Inke R.
König,
Gereon
Hüttmann, and
Johann
Roider,
Self-examination low-cost full-field OCT (SELFF-OCT) for patients with various macular diseases, Graefe's Archive for Clinical and Experimental Ophthalmology , Dez. 2020.
Self-examination low-cost full-field OCT (SELFF-OCT) for patients with various macular diseases, Graefe's Archive for Clinical and Experimental Ophthalmology , Dez. 2020.
Datei: | s00417-020-05035-6 |
Bibtex: | ![]() @article{von-derBurchard2020, author = {von der Burchard, C;Moltmann, M.;Tode, J;Ehlken, C;Sudkamp, H;Theisen-Kunde, D;König, I;Hüttmann, G and Roider, J}, title = {Self-examination low-cost full-field OCT (SELFF-OCT) for patients with various macular diseases}, journal = {Graefe's Archive for Clinical and Experimental Ophthalmology}, ISSN = {1435-702X}, url = {https://doi.org/10.1007/s00417-020-05035-6}, year = {2020}, type = {Journal Article} } |
Dierck
Hillmann,
Clara
Pfäffle,
Hendrik
Spahr,
Helge
Sudkamp,
Gesa
Franke, and
Gereon
Hüttmann,
In Vivo FF-SS-OCT Optical Imaging of Physiological Responses to Photostimulation of Human Photoreceptor Cells, in High Resolution Imaging in Microscopy and Ophthalmology: New Frontiers in Biomedical Optics , Bille, Josef F., Eds. Cham: Springer International Publishing, 2019, pp. 181-194.
In Vivo FF-SS-OCT Optical Imaging of Physiological Responses to Photostimulation of Human Photoreceptor Cells, in High Resolution Imaging in Microscopy and Ophthalmology: New Frontiers in Biomedical Optics , Bille, Josef F., Eds. Cham: Springer International Publishing, 2019, pp. 181-194.
ISBN: | 978-3-030-16638-0 |
Datei: | 978-3-030-16638-0_8 |
Bibtex: | ![]() @inbook{Hillmann2019, author = {Hillmann, Dierck;Pfäffle, Clara;Spahr, Hendrik;Sudkamp, Helge;Franke, Gesa and Hüttmann, Gereon}, title = {In Vivo FF-SS-OCT Optical Imaging of Physiological Responses to Photostimulation of Human Photoreceptor Cells}, booktitle = {High Resolution Imaging in Microscopy and Ophthalmology: New Frontiers in Biomedical Optics}, editor = {Bille, Josef F.}, publisher = {Springer International Publishing}, address = {Cham}, pages = {181-194}, ISBN = {978-3-030-16638-0}, url = {https://doi.org/10.1007/978-3-030-16638-0_8}, year = {2019}, type = {Book Section} } |
Helge
Sudkamp,
Dierck
Hillmann,
Peter
Koch,
Malte
vom Endt,
Hendrik
Spahr,
Michael
Münst,
Clara
Pfäffle,
Reginald
Birngruber, and
Gereon
Hüttmann,
Simple approach for aberration-corrected OCT imaging of the human retina, Opt Lett , vol. 43, no. 17, pp. 4224, 08 2018.
Simple approach for aberration-corrected OCT imaging of the human retina, Opt Lett , vol. 43, no. 17, pp. 4224, 08 2018.
DOI: | 10.1364/ol.43.004224 |
Bibtex: | ![]() @article{Sudkamp2018a, author = {Sudkamp, H; Hillmann, D; Koch, P;vom Endt, M; Spahr, H; Münst, M; Pfäffle, C; Birngruber, R and Hüttmann, G}, title = {Simple approach for aberration-corrected OCT imaging of the human retina}, journal = {Opt Lett}, pages = {4224}, ISSN = {0146-9592 1539-4794}, DOI = {10.1364/ol.43.004224}, year = {2018}, type = {Journal Article}, keyword = {Retome} } |
Clara
Pfäffle,
Hendrik
Spahr,
Dierck
Hillmann,
Helge
Sudkamp,
Gesa
Franke,
Peter
Koch, and
Gereon
Hüttmann,
Reduction of frame rate in full-field swept-source optical coherence tomography by numerical motion correction [Invited], Biomedical Optics Express , vol. 8, no. 3, pp. 1499-1511, 03 2017.
Reduction of frame rate in full-field swept-source optical coherence tomography by numerical motion correction [Invited], Biomedical Optics Express , vol. 8, no. 3, pp. 1499-1511, 03 2017.
DOI: | 10.1364/BOE.8.001499 |
Weblink: | https://doi.org/10.1364/BOE.8.001499 |
Datei: | abstract.cfm |
Bibtex: | ![]() @article{Pfäffle2017, author = {Pfäffle, Clara and Spahr, Hendrik and Hillmann, Dierck and Sudkamp, Helge and Franke, Gesa and Koch, Peter and Hüttmann, Gereon}, title = {Reduction of frame rate in full-field swept-source optical coherence tomography by numerical motion correction [Invited]}, journal = {Biomedical Optics Express}, volume = {8}, number = {3}, pages = {1499-1511}, keywords = {Image reconstruction-restoration Optical coherence tomography}, url = {http://www.osapublishing.org/boe/abstract.cfm?URI=boe-8-3-1499}, year = {2017}, type = {Journal Article} } |
Helge
Sudkamp,
Peter
Koch,
Hendrik
Spahr,
Dierck
Hillmann,
Gesa
Franke,
Michael
Münst,
Fred
Reinholz,
Reginald
Birngruber, and
Gereon
Hüttmann,
In-vivo retinal imaging with off-axis full-field time-domain optical coherence tomography, Optics Letters , vol. 41, no. 21, pp. 4987-4990, Nov. 2016.
In-vivo retinal imaging with off-axis full-field time-domain optical coherence tomography, Optics Letters , vol. 41, no. 21, pp. 4987-4990, Nov. 2016.
DOI: | 10.1364/OL.41.004987 |
Datei: | abstract.cfm |
Bibtex: | ![]() @article{RN4897, author = {Sudkamp, Helge and Koch, Peter and Spahr, Hendrik and Hillmann, Dierck and Franke, Gesa and Münst, Michael and Reinholz, Fred and Birngruber, Reginald and Hüttmann, Gereon}, title = {In-vivo retinal imaging with off-axis full-field time-domain optical coherence tomography}, journal = {Optics Letters}, volume = {41}, number = {21}, pages = {4987-4990}, DOI = {10.1364/OL.41.004987}, url = {http://ol.osa.org/abstract.cfm?URI=ol-41-21-4987}, year = {2016}, type = {Journal Article} } |
Hendrik
Spahr,
Dierck
Hillmann,
Carola
Hain,
Clara
Pfäffle,
Helge
Sudkamp,
Gesa
Franke,
Peter
Koch, and
Gereon
Hüttmann,
Darstellung von Blutfluss und Pulsation in retinalen Gefäßen mit Full-Field-Swept-Source-OCT, Klin Monatsbl Augenheilkd , vol. 233, no. 12, pp. 1324-1330, Okt. 2016.
Darstellung von Blutfluss und Pulsation in retinalen Gefäßen mit Full-Field-Swept-Source-OCT, Klin Monatsbl Augenheilkd , vol. 233, no. 12, pp. 1324-1330, Okt. 2016.
DOI: | 10.1055/s-0042-120279 |
Bibtex: | ![]() @article{Spahr2016, author = {Spahr, H. and Hillmann, D. and Hain, C. and Pfäffle, C. and Sudkamp, H. and Franke, G. and Koch, P. and Hüttmann, G.}, title = {Darstellung von Blutfluss und Pulsation in retinalen Gefäßen mit Full-Field-Swept-Source-OCT}, journal = {Klin Monatsbl Augenheilkd}, volume = {233}, number = {12}, pages = {1324-1330}, ISSN = {0023-2165}, DOI = {10.1055/s-0042-120279}, year = {2016}, type = {Journal Article} } |
Dierck
Hillmann,
Hendrik
Spahr,
Carola
Hain,
Helge
Sudkamp,
Gesa
Franke,
Clara
Pfäffle,
Christian
Winter, and
Gereon
Hüttmann,
Aberration-free volumetric high-speed imaging of in vivo retina, Scientific Reports , vol. 6, pp. 1-11, 2016.
Aberration-free volumetric high-speed imaging of in vivo retina, Scientific Reports , vol. 6, pp. 1-11, 2016.
Datei: | srep35209 |
Bibtex: | ![]() @article{Hillmann2016, author = {Hillmann, Dierck and Spahr, Hendrik and Hain, Carola and Sudkamp, Helge and Franke, Gesa and Pfäffle, Clara and Winter, Christian and Hüttmann, Gereon}, title = {Aberration-free volumetric high-speed imaging of in vivo retina}, journal = {Scientific Reports}, volume = {6}, pages = {1-11}, url = {http://dx.doi.org/10.1038/srep35209}, year = {2016}, type = {Journal Article} } |
Dierck
Hillmann,
Hendrik
Spahr,
Clara
Pfäffle,
Helge
Sudkamp,
Gesa
Franke, and
Gereon
Hüttmann,
In vivo optical imaging of physiological responses to photostimulation in human photoreceptors, PNAS Early Edition , pp. 1-6, 2016.
In vivo optical imaging of physiological responses to photostimulation in human photoreceptors, PNAS Early Edition , pp. 1-6, 2016.
Datei: | 1606428113.abstract |
Bibtex: | ![]() @article{Hillmann2016, author = {Hillmann, Dierck and Spahr, Hendrik and Pfäffle, Clara and Sudkamp, Helge and Franke, Gesa and Hüttmann, Gereon}, title = {In vivo optical imaging of physiological responses to photostimulation in human photoreceptors}, journal = {PNAS Early Edition}, pages = {1-6}, abstract = {Noninvasive functional imaging of molecular and cellular processes of vision may have immense impact on research and clinical diagnostics. Although suitable intrinsic optical signals (IOSs) have been observed ex vivo and in immobilized animals in vivo, detecting IOSs of photoreceptor activity in living humans was cumbersome and time consuming. Here, we observed clear spatially and temporally resolved changes in the optical path length of the photoreceptor outer segment as a response to an optical stimulus in the living human eye. To witness these changes, we evaluated phase data obtained with a parallelized and computationally aberration-corrected optical coherence tomography system. The noninvasive detection of optical path length changes shows neuronal photoreceptor activity of single cones in living human retina, and therefore, it may provide diagnostic options in ophthalmology and neurology and could provide insights into visual phototransduction in humans.}, url = {http://www.pnas.org/content/early/2016/10/10/1606428113.abstract}, year = {2016}, type = {Journal Article} } |
Hendrik
Spahr,
Dierck
Hillmann,
Carola
Hain,
Clara
Pfäffle,
Helge
Sudkamp,
Gesa
Franke, and
Gereon
Hüttmann,
Imaging vascular dynamics in human retina using full-field swept-source optical coherence tomography (Conference Presentation), 2016. pp. 96970E-96970E-1.
Imaging vascular dynamics in human retina using full-field swept-source optical coherence tomography (Conference Presentation), 2016. pp. 96970E-96970E-1.
DOI: | 10.1117/12.2214303 |
Datei: | 12.2214303 |
Bibtex: | ![]() @inproceedings{Spahr2016, author = {Spahr, Hendrik and Hillmann, Dierck and Hain, Carola and Pfäffle, Clara and Sudkamp, Helge and Franke, Gesa and Hüttmann, Gereon}, title = {Imaging vascular dynamics in human retina using full-field swept-source optical coherence tomography (Conference Presentation)}, volume = {9697}, pages = {96970E-96970E-1}, note = {10.1117/12.2214303}, abstract = {We demonstrate a new non-invasive method to assess the functional condition of the retinal vascular system. Phase-sensitive full-field swept-source optical coherence tomography (PhS-FF-SS-OCT) is used to investigate retinal vascular dynamics at unprecedented temporal resolution. Motion of retinal tissue, that is induced by expansion of the vessels therein, is measured with an accuracy of about 10 nm. The pulse shape of arterial and venous pulsation, their temporal delay as well as the frequency dependent pulse propagation through the capillary bed are determined. For the first time, imaging speed and motion sensitivity are sufficient for a direct measurement of pulse waves propagating with more than 600 mm/s in retinal vessels of a healthy young subject.}, url = {http://dx.doi.org/10.1117/12.2214303}, type = {Conference Proceedings}, year = { 2016} } |
Hendrik
Spahr,
Dierck
Hillmann,
Carola
Hain,
Clara
Pfäffle,
Helge
Sudkamp,
Gesa
Franke, and
Gereon
Hüttmann,
Imaging pulse wave propagation in human retinal vessels using full-field swept-source optical coherence tomography, Optics Letters , vol. 40, no. 20, pp. 4771-4774, Okt. 2015.
Imaging pulse wave propagation in human retinal vessels using full-field swept-source optical coherence tomography, Optics Letters , vol. 40, no. 20, pp. 4771-4774, Okt. 2015.
DOI: | 10.1364/OL.40.004771 |
Datei: | abstract.cfm |
Bibtex: | ![]() @article{Spahr2015, author = {Spahr, Hendrik and Hillmann, Dierck and Hain, Carola and Pfäffle, Clara and Sudkamp, Helge and Franke, Gesa and Hüttmann, Gereon}, title = {Imaging pulse wave propagation in human retinal vessels using full-field swept-source optical coherence tomography}, journal = {Optics Letters}, volume = {40}, number = {20}, pages = {4771-4774}, abstract = {We demonstrate a new noninvasive method to assess biomechanical properties of the retinal vascular system. Phase-sensitive full-field swept-source optical coherence tomography (PhS-FF-SS-OCT) is used to investigate retinal vascular dynamics at unprecedented temporal resolution. The motion of retinal tissue that is induced by expansion of the vessels therein is measured with an accuracy of about 10 nm. The pulse shapes of arterial and venous pulsations, their temporal delays, as well as the frequency-dependent pulse propagation through the capillary bed, are determined. For the first time, imaging speed and motion sensitivity are sufficient for a direct measurement of pulse waves propagating with more than 600 mm/s in retinal vessels of a healthy young subject.}, keywords = {Optical coherence tomography Ophthalmology Time-resolved imaging Functional monitoring and imaging}, DOI = {10.1364/OL.40.004771}, url = {http://ol.osa.org/abstract.cfm?URI=ol-40-20-4771}, year = {2015}, type = {Journal Article} } |
Hendrik
Spahr,
Carola
Hain,
Helge
Sudkamp,
Gesa
Franke,
Dierck
Hillmann, and
Gereon
Hüttmann,
Functional Microangiography of in vivo human retina by Full-Field OCT, Investigative Ophthalmology & Visual Science , vol. 56, no. 7, pp. 5974-5974, 2015.
Functional Microangiography of in vivo human retina by Full-Field OCT, Investigative Ophthalmology & Visual Science , vol. 56, no. 7, pp. 5974-5974, 2015.
Weblink: | https://iovs.arvojournals.org/article.aspx?articleid=2336064 |
Datei: | |
Bibtex: | ![]() @article{Spahr2015, author = {Spahr, Hendrik and Hain, Carola and Sudkamp, Helge and Franke, Gesa and Hillmann, Dierck and Huttmann, Gereon}, title = {Functional Microangiography of in vivo human retina by Full-Field OCT}, journal = {Investigative Ophthalmology & Visual Science}, volume = {56}, number = {7}, pages = {5974-5974}, abstract = { PurposeOCT based functional microangiography of the retina requires high speed acquisition of a large number of volumetric datasets. Imaging speed of conventional scanning OCT devices is limited by the applicable radiant power and the mechanics used to scan the focused beam over the desired field of view. Full-Field Swept-Source OCT (FF-SS-OCT) resolves both issues, using an areal illumination, which dramatically increases the allowed amount of radiation, and an ultrafast camera for a highly parallelized acquisition. MethodsThe retina of healthy volunteers was illuminated with wavelengths between 816 and 867 nm by the extended beam of a tunable laser (Broadsweeper, Superlum). Retinal irradiance was below the maximum permissable exposure (MPE). Light backscattered from the retina was imaged onto an ultrafast CMOS camera (SA-Z, Photron), where it interfered with an extended reference beam. From a series of interference images at different wavelengths, volumetric OCT images of the retina were reconstructed. ResultsWe demonstrate in vivo retinal imaging at 9.9 billion voxels per second (40 million A-scans/s with 256 axial pixels). Sacrificing depth resolution by reducing the number of axial pixels, the A-scan rate was increased to more than 1 billion A-scans per second. FF-SS-OCT allowed imaging of all important retinal structures with good quality at unprecedented imaging speed (see fig. 1). Fast volumetric imaging at up to 3000 volumes/s was used to visualize small capillaries and to analyze the pulsation of retinal arteries and veins (see fig. 2). Imaging time for an area of 4 mm x 2 mm (896 x 368 A-scans) was only 316 µs. The high volume rate and the inherent phase stability enabled quantitative measurement of the change of retinal thickness due to blood pulsation with approx. 10 nm precision. A delay of the venous pulsation with respect to the arteries was observed (approx. 11 ms). The amplitudes of higher frequency components of the venous pulsation were considerably attenuated. ConclusionsFF-SS-OCT provides fast volumetric imaging of the retina with good image quality. The capillary network can be analyzed with high spatial and temporal resolution. Analysis of retinal pulsation may provide information on pathological changes of vessels and capillaries. Angiographic OCT acquired with the FF-SS-OCT setup. Functional angiography showing the pulsation of retinal artery and vein.}, ISSN = {1552-5783}, url = {http://dx.doi.org/}, year = {2015}, type = {Journal Article} } |
Livia
Zarnescu,
Michael C.
Leung,
Michael
Abeyta,
Helge
Sudkamp,
Thomas
Baer,
Barry
Behr, and
Audrey K.
Ellerbee,
Label-free characterization of vitrification-induced morphology changes in single-cell embryos with full-field optical coherence tomography, Journal of Biomedical Optics , vol. 20, no. 9, pp. 096004-096004, 2015.
Label-free characterization of vitrification-induced morphology changes in single-cell embryos with full-field optical coherence tomography, Journal of Biomedical Optics , vol. 20, no. 9, pp. 096004-096004, 2015.
DOI: | 10.1117/1.JBO.20.9.096004 |
Datei: | 1.JBO.20.9.096004 |
Bibtex: | ![]() @article{Zarnescu2015, author = {Zarnescu, Livia and Leung, Michael C. and Abeyta, Michael and Sudkamp, Helge and Baer, Thomas and Behr, Barry and Ellerbee, Audrey K.}, title = {Label-free characterization of vitrification-induced morphology changes in single-cell embryos with full-field optical coherence tomography}, journal = {Journal of Biomedical Optics}, volume = {20}, number = {9}, pages = {096004-096004}, note = {10.1117/1.JBO.20.9.096004}, abstract = {Abstract. Vitrification is an increasingly popular method of embryo cryopreservation that is used in assisted reproductive technology. Although vitrification has high post-thaw survival rates compared to other freezing techniques, its long-term effects on embryo development are still poorly understood. We demonstrate an application of full-field optical coherence tomography (FF-OCT) to visualize the effects of vitrification on live single-cell (2 pronuclear) mouse embryos without harmful labels. Using FF-OCT, we observed that vitrification causes a significant increase in the aggregation of structures within the embryo cytoplasm, consistent with reports in literature based on fluorescence techniques. We quantify the degree of aggregation with an objective metric, the cytoplasmic aggregation (CA) score, and observe a high degree of correlation between the CA scores of FF-OCT images of embryos and of fluorescence images of their mitochondria. Our results indicate that FF-OCT shows promise as a label-free assessment of the effects of vitrification on embryo mitochondria distribution. The CA score provides a quantitative metric to describe the degree to which embryos have been affected by vitrification and could aid clinicians in selecting embryos for transfer.}, ISSN = {1083-3668}, DOI = {10.1117/1.JBO.20.9.096004}, url = {http://dx.doi.org/10.1117/1.JBO.20.9.096004}, year = {2015}, type = {Journal Article} } |
Hee Yoon
Lee,
Helge
Sudkamp,
Tahereh
Marvdashti, and
Audrey K.
Ellerbee,
Interleaved optical coherence tomography, Optics Express , vol. 21, no. 22, pp. 26542-26556, 2013.
Interleaved optical coherence tomography, Optics Express , vol. 21, no. 22, pp. 26542-26556, 2013.
DOI: | 10.1364/OE.21.026542 |
Datei: | abstract.cfm |
Bibtex: | ![]() @article{Lee2013, author = {Lee, Hee Yoon and Sudkamp, Helge and Marvdashti, Tahereh and Ellerbee, Audrey K.}, title = {Interleaved optical coherence tomography}, journal = {Optics Express}, volume = {21}, number = {22}, pages = {26542-26556}, abstract = {We present a novel and cost-effective technique – interleaved optical coherence tomography (iOCT) – to enhance the imaging speed of swept source OCT systems by acquiring data from multiple lateral positions simultaneously during a single wavelength sweep, using a single detector and a virtually imaged phase array (VIPA) as a multi-band demultiplexer. This technique uses spectral encoding to convert coherence length into higher imaging speed; the speed enhancement factor is independent of the source speed or center wavelength, and the effective A-scan rate scales linearly with sweep speed. The optical configuration requires only a change in the sample arm of a traditional OCT system and preserves the axial resolution and fall-off characteristic of a traditional SS-OCT using the same light source. Using 10kHz, 20kHz and 100kHz sources we provide a first demonstration of image speed enhancement factors of up to 12, 6 and 10, respectively, which yield effective A-scan rates of 120kHz, 120kHz and 1MHz for B-scan imaging, with a sensitivity of up to 82.5 dB. We also show that iOCT can image faster dynamics than traditional OCT B-scan imaging and is capable of 3D biological imaging. The iOCT concept suggests a new route to high-speed OCT imaging for laser developers: that is, by focusing on improving the coherence length and linewidth of existing and emerging sources. Hence, iOCT is a nice complement to ongoing research and commercial efforts to enable faster imaging through development of lasers with faster sweep rates, and offers new hope for existing sources with slow sweep rates and potential for enhancement of coherence length to compete with faster sources to achieve high-speed OCT.}, keywords = {Optical design of instruments Imaging systems Coherence imaging Optical coherence tomography Optical diagnostics for medicine}, DOI = {10.1364/OE.21.026542}, url = {http://www.opticsexpress.org/abstract.cfm?URI=oe-21-22-26542}, year = {2013}, type = {Journal Article} } |
Helge
Sudkamp,
H Y
Lee,
Gereon
Hüttmann, and
A K
Kellerbee,
An approach to increase the speed of Optical Coherence Tomography using a Virtually Imaged Phased Array, in Studierendentagung , Universität zu Lübeck, 2013.
An approach to increase the speed of Optical Coherence Tomography using a Virtually Imaged Phased Array, in Studierendentagung , Universität zu Lübeck, 2013.